The study examined the factors affecting agribusiness success among participants of International Institute of Tropical Agriculture (IITA) youth agribusiness programme in Nigeria. For the purpose of this research, non-probability sampling technique (Convenience) was adopted and the entire population of 117 was given the questionnaire but 110 respondents responded adequately. The study concludes that the following are the major factors (constraints) affecting the participants of IYA programme: lack of adequate storage facilities, lack of adequate processing facilities, lack of adequate government support, technological factors, power interruptions, loan application procedures of banks and other lending institutions are too complicated, high interest rate charged by banks and other leading institutions, and inadequacy of credit institutions. It was recommended that storage and processing facilities for agricultural/agribusiness inputs and products should be adequately provided, electricity (power/energy) that will adequately enhance the agribusiness activities should be provided, and also Government should be more involved in reducing the interest rate on bank loans advanced to agribusinesses through commercial banks.