Acute pancreatitis is a serious and potentially fatal condition, caused by the pancreas self-digesting with its own accidentally activated enzymes. its diagnosis is based on a combination of clinical, biological and radiological evidence. The absence of lipase elevation during acute pancreatitis is extremely rare and can sometimes make the diagnosis difficult and therefore delay the treatment. We will report the case of a 27-year-old female patient, with no previous history of the disease, who consulted us for acute abdominal pain, and whose diagnosis, after an etiological investigation, was pancreatitis with normal lipase levels.