This survey demonstrates that normal glucose regulation is less common than abnormal glucose regulation in patients with CAD. OGTT easily discloses the glucometabolic state and should be a routine procedure. The knowledge of glucometabolic state among these patients should influence their future management because it has great potential to improve the outcome.
Abnormal glucose tolerance is a strong risk factor for future cardiovascular events after myocardial infarction. Since it is common and possible to detect even during the hospital phase it may be a target for novel secondary preventive efforts.
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Coronary artery disease and type 2 diabetes are chronic diseases of substantial and growing prevalence. Their coincidence is common, markedly enhancing mortality and morbidity. The risk for cardiovascular disease increases along a spectrum of blood glucose concentrations already apparent at levels regarded as normal. Accordingly, strategies for the early detection of glucometabolic disturbances are needed to find ways to prevent the occurrence of cardiovascular complications or to treat them already at an early stage. More specifically, abnormal glucose tolerance is almost twice as common amongst patients with a myocardial infarction as in population‐based controls and a normal glucose regulation is indeed less common than abnormal glucose metabolism also amongst patients with stable coronary artery disease. Already an abnormal glucose tolerance is a strong risk factor for future cardiovascular events after an acute myocardial infarction. An oral glucose tolerance test should, therefore, be a part of the evaluation of total risk in all patients with coronary artery disease. As glucose disturbances are common and easy to detect, they may be suitable targets for novel secondary preventive efforts.
Ниже приведены классы рекомендаций и уровни доказательств, на основании которых члены рабочей группы оценивали пользу и эффективность различных вмешательств. Введение Сахарный диабет (СД) и сердечно-сосудистые заболевания (ССЗ) часто оказываются разными сторонами одной монеты: СД считают эквивалентом коронарной болезни сердца (КБС) и, наоборот, многие пациенты с КБС страдают СД или преддиабетом. В связи с этим для диабетологов и кардиологов пришло время объединить свои усилия, чтобы улучшить качество медицинской помощи миллионам больных сердечно-сосудистыми и метаболическими заболеваниями. Европейское общество кардиологов и Европейская ассоциация по изучению диабета разработали рекомендации по ведению пациентов с СД и ССЗ. Рабочей группой экспертов предложен алгоритм обследования пациентов (рис. 1), который должен помочь диагностике ССЗ у больных СД и выявлять метаболические нару-РЕКОМЕНДАЦИИ ПО ЛЕЧЕНИЮ Рациональная Фармакотерапия в Кардиологии 2007;№4 71 Рабочая группа по диабету и сердечно-сосудистым заболеваниям Европейского общества кардиологов и Европейской ассоциации по изучению диабета
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