В работе дана сравнительная характеристика секреторной диареи, вызванной энтеропатогенной группой эшерихиозов и ротавирусом у детей раннего возраста.

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This article gives a comparative description of the clinical and epidemiological characteristics of rotavirus infection in children under 1 year and 1–3 years old. An analysis of 83 case histories of the examined children for rotavirus infection under the age of 3 years was carried out. Patients were divided into 2 groups: group 1 — children under 1-year-old (48 patients), group 2 — children from 1 to 3 years old (35 patients). As a result of the study, it was found that in children of the 1st group, rotavirus infection proceeded predominantly (Р˂0.01) in the form of severe enteritis (71.0%), in combination with bacterial intestinal infection (75.0%), with significant (P ˂0.05) frequent (31.3%) bloating due to profuse watery diarrhea. In children of this group in 4.0% of cases, the disease was fatal. In the vast majority (96.7%) of children of the 2nd group, rotavirus infection proceeded in the form of gastroenteritis, with almost the same ratio of moderate to severe forms (47.0, 50.0%). Due to large losses with repeated vomiting and loose stools, significantly (Р˂0.01) more often (53.3%) there was a decrease in urine output and an increase in creatinine level (40.0%).

In this article, the practical significance of determining markers of inflammation (blood procalcitonin, fecal calprotectin, fecal lactoferrin) for distinguishing infectious secretory from infectious invasive diarrhea, as well as from functional diarrhea of non-infectious genesis, is given in the article. A survey was conducted of 54 children aged 0 to 3 years hospitalized in an infectious disease’s hospital with secretory viral diarrhea (rotavirus, astro-, adeno-, noro-, and enterovirus), for the period 2019–2020.

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