The chemistry of 2-aroylbenzofurans and their derivatives has been investigated, and some of the compounds showed estrogenic activity. The RapStoermer benzofuran cvclisation was successfully extended t o o-hydroxy-ketones, including khelhone (5-acetyl-6-hydroxy-4 : 7-dimethoxybenzofuran), and several 2-aroyl-4 : 7-dimethosy-3-methylbenzo[l: 2-b, 4 : 541difurans were prepared. Part 111, preceding paper.
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