Management of produced water from conventional plays and shale and tight oil and gas plays is driving subtle yet potentially consequential changes in certain regions and Underground Injection Control (UIC) formations. UIC operation topics of interest include induced seismicity (from UIC injection, extraction, or unknown/anomolous activity), formation pressurization from years of UIC injection, and reallocation of produced water from originating "tight" producing formations to more receptive conventional, depleted, or waterflooded formations, resulting in formation pressure changes. Early signs of diminished formation health or threats to operations continuity can include: Barely felt (low magnitude) induced and anomolous earthsquakes - which nonetheless are a cause of significant concern to the public – and by extension, landowners, stakeholders, and regulators.Reduced formation injectivity – suggesting that injection rates should be "dialed back", or that injection pump pressures be increased, or that water be transported further to more receptive injection formations. If encountered, stresses can contribute to cost overruns, impairment to operations schedules, additional oversite to assure regulatory compliance, reduced public goodwill, and potentially, impairment of industry’s social license to operate. Through analysis of publicly available UIC operations data and well completion data, we evaluate methods which might help to qualitatively assess UIC issues with macro, regional, local and subsurface formation perspectives. The methods discussed may provide operators with a consistent simple methodology to qualitatively identify those assets and UIC formations with higher potential relative risk which may warrant more detailed exploration and possible risk mitigation.