Objective: To assess the clinico-radiological outcome of the fusion in anterior cervical decompression and fusion surgeries. Methods: This was a prospective cross-sectional study. Patients operated through anterior approach for cervical spine disease were included in the study. Patients were operated through anterior approach by employing Smith Robinson's technique or Cloward technique (on the basis of surgeon's preference). Inter body grafts used were iliac crest autograft, artificial G graft from Surgiwear Company. Subjective clinical evaluation was assessed by axial pain and Odom's criteria. Nurick grade was used to evaluate improvement in neurological myelopathic status. Results: A total of 62 patients were included in the study. Majority of them were males (80.6%). Majority of them were males (80.6%). Most common age group was 31-40 years. Of the three main group of disease features, degenerative was most common (64.5%). C5/6 disc space was the commonest operated level (64.5%). Iliac crest bone graft was used primarily (46/62=74%) for fusion purpose. Partial anterior graft migration (19.4%) was the most common post-op complication. The subjective assessment of improvement was excellent in 16.1% patients and good was in 45.2%. Conclusion:Best clinico-radiological improvement was found in degenerative group followed by inflammatory and traumatic.