This investigation aims to measure the elemental concentrations of sea water samples from the Gulf of Aqaba along the Saudi seashore. Seventy elements were investigated using the Inductively Coupled Plasma Mass Spectrometry (ICP-MS) technique. Sixty samples were collected starting from Ad Dorah city at the national border between Saudi Arabia and Jordan to Ra's Al-Sheikh Humayed at the south of Aqaba Gulf. Elemental concentrations of major, trace, toxic, and radioactive sources in this area are measured. The results represent a database for many vital areas of interest.