This work analyses the role of proteoglycans on skin ageing, influenced by the presence of glycosylated proteins, which exercise diverse functions on the skin. They are essential components that restore the cells, providing hydration, maintaining hydration of the extracellular matrix, preventing the formation of wrinkles thanks to their ability to combine to other molecules such as collagen or hyaluronic acid and favouring the smoothness of the skin texture. The use of these proteins is a very recent and promising topic, since their application may revolutionize skin ageing therapies. Of the existing proteoglycans, decorin, versican and perlecan are of special note, playing a fundamental role on skin. R esum e Nous avons analys e dans cette etude le rôle des prot eoglycanes dans le vieillissement de la peau, conditionn e par la pr esence des prot eines glycosyl ees qui exercent plusieurs fonctions sur la peau. Ce sont des composants essentiels qui restaurent les cellules, fournissent de l'hydratation en maintenant l'hydratation de la matrice extracellulaire en evitant la formation de rides cutan ees grâce a sa capacit e de se combiner a d'autres mol ecules tels que le collag ene ou l'acide hyaluronique qui favorisent la douceur de la peau. L'utilisation de ces prot eines est un des sujets les plus r ecents et prometteurs, etant donn e que son application peut repr esenter une r evolution quant aux th erapies qui luttent contre le vieillissement cutan e. Parmi les prot eoglycanes ressortent la d ecorine, le versicane et le perl ecane qui jouent un rôle fondamental sur le derme.
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