SUMMARY.— The association of vitiligo with organ‐specific autoimmune disorders has been examined with particular reference to pernicious anaemia. A significantly increased incidence of gastric parietal cell antibody was found in serum of sixty‐two patients with vitiligo. There is now sufficient clinical and investigative evidence to suggest that absence of melanocytes from lesions of vitiligo results from immunological disturbance.

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Summary.— “Perioral dermatitis” has been studied in 29 patients; all were females in their child‐bearing years, with ages ranging from 18 to 39 (mean 27). Twenty patients showed a marked flushing tendency, but the condition was apparently unrelated to other factors studied, including colouring, skin type, pregnancy and the contraceptive pill. Perioral dermatitis is a distinct entity and not a variant of seborrhoeic derma‐titis or rosacea. All patients were greatly improved by tetracycline therapy for 2–3 months, after which relapse was unusual.

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