No abstract

No abstract

0.01; obstruction, P=0.047). Also, consumption of water by group 2 was greater than that by group 1 The aim of the present study was to evaluate the (P=0.049). No statistically significant differences were effects of neostigmine as a final anaesthetic manfound between the diameters of the colon (pre-and oeuvre on colonic anastomoses. A colonic anapost-anastomosis), or with respect to general adstomosis was constructed in 40 Sprague-Dawley rats.hesions and adhesions to the anastomotic line. No The animals were divided into two groups: (1) rats significant differences were found between anreceiving intravenous saline solution (placebo); and (2) astomotic resistance (determined in terms of bursting rats receiving an intravenous injection of neostigmine.pressure and bursting wall tension) in the two groups. The size of the caecum, and the diameters of the pre-The inclusion of neostigmine in an anaesthetic proanastomotic and post-anastomotic colon were meastocol under experimental setting did not reduce the ured during the operation and 4 days after surgery, resistance of colonic anastomoses and did not comwhen all the animals were sacrificed. At this time, the promise normal healing. Moreover, obstruction presence of adhesions was also investigated. Each caused by peristaltic weakness might be prevented by segment containing an anastomosis was removed, the expulsion of stool that is induced by the strong and the bursting pressure and bursting wall tension contraction of the colonic smooth muscle. were determined. Loss of caecum diameter was significantly greater in group 2 than in group 1 (P= Keywords: neostigmine, colonic anastomosis, anastomosis healing, anastomosis resistance, intestinal 0.03). Dilatation and obstruction of the colon were significantly more frequent in group 1 (dilatation, P= obstruction.

0.01; obstruction, P=0.047). Also, consumption of water by group 2 was greater than that by group 1 The aim of the present study was to evaluate the (P=0.049). No statistically significant differences were effects of neostigmine as a final anaesthetic manfound between the diameters of the colon (pre-and oeuvre on colonic anastomoses. A colonic anapost-anastomosis), or with respect to general adstomosis was constructed in 40 Sprague-Dawley rats.hesions and adhesions to the anastomotic line. No The animals were divided into two groups: (1) rats significant differences were found between anreceiving intravenous saline solution (placebo); and (2) astomotic resistance (determined in terms of bursting rats receiving an intravenous injection of neostigmine.pressure and bursting wall tension) in the two groups. The size of the caecum, and the diameters of the pre-The inclusion of neostigmine in an anaesthetic proanastomotic and post-anastomotic colon were meastocol under experimental setting did not reduce the ured during the operation and 4 days after surgery, resistance of colonic anastomoses and did not comwhen all the animals were sacrificed. At this time, the promise normal healing. Moreover, obstruction presence of adhesions was also investigated. Each caused by peristaltic weakness might be prevented by segment containing an anastomosis was removed, the expulsion of stool that is induced by the strong and the bursting pressure and bursting wall tension contraction of the colonic smooth muscle. were determined. Loss of caecum diameter was significantly greater in group 2 than in group 1 (P= Keywords: neostigmine, colonic anastomosis, anastomosis healing, anastomosis resistance, intestinal 0.03). Dilatation and obstruction of the colon were significantly more frequent in group 1 (dilatation, P= obstruction.

The goal of this study was to examine the relationship between the effects of spleen transplantation on the acceptance of a skin allograft from the same donor and the detection of donor chimerism in recipient tissues. Male Sprague-Dawley rats and female Wistar rats were used as donors and recipients, respectively. Four experimental groups were established: group C: only skin grafting was performed; group S: recipients were splenectomized before skin grafting; group 1: skin grafts were performed immediately after splenectomy of recipients and spleen transplantation, and group 2: splenectomy of the recipients and spleen grafting were performed 48 h before skin grafting. All animals were sacrificed 14 weeks after surgery. The rate of acceptance of skin grafts was significantly higher in animals that received both skin and spleen transplantations than in group C (p = 0.03) or in group S (p = 0.04). Detection of donor chimeric cells was significantly more frequent in rats after spleen transplantation than in group C (p = 0.03). However, the detection of chimeric cells was not related to the acceptance of skin grafts. To conclude, the beneficial effect of spleen auxiliary transplantation on allograft survival was not related to the detection of long-term chimerism in the recipient’s tissues.