The aim of this study was to estimate the incidence of COVID-19 disease in the French national population of dialysis patients, their course of illness and to identify the risk factors associated with mortality. Our study included all patients on dialysis recorded in the French REIN Registry in April 2020. Clinical characteristics at last follow-up and the evolution of COVID-19 illness severity over time were recorded for diagnosed cases (either suspicious clinical symptoms, characteristic signs on the chest scan or a positive reverse transcription polymerase chain reaction) for SARS-CoV-2. A total of 1,621 infected patients were reported on the REIN registry from March 16th, 2020 to May 4th, 2020. Of these, 344 died. The prevalence of COVID-19 patients varied from less than 1% to 10% between regions. The probability of being a case was higher in males, patients with diabetes, those in need of assistance for transfer or treated at a self-care unit. Dialysis at home was associated with a lower probability of being infected as was being a smoker, a former smoker, having an active malignancy, or peripheral vascular disease. Mortality in diagnosed cases (21%) was associated with the same causes as in the general population. Higher age, hypoalbuminemia and the presence of an ischemic heart disease were statistically independently associated with a higher risk of death. Being treated at a selfcare unit was associated with a lower risk. Thus, our study showed a relatively low frequency of COVID-19 among dialysis patients contrary to what might have been assumed.

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Conclusions: Volume overload in PD is associated with need for more antihypertensives and greater intraindividual BP variability. BIA could be used to detect covert volume overload and optimize the assessment of prescribed "dry weight" and the use of antihypertensives without excessive BP variability.

vs 13.4% p = 0.001), however the percentage of the population with TSH at a critical value $20 mlU/L was similar in both groups (2.4%).When comparing GFR according to TSH values, a significant difference was found in renal function in subjects with TSH $20 compared to the other groups (79.2AE31 vs 92.6AE30 ml/min p=#0.001). Furthermore, FT3 levels decreased directly in relation to the lower degree of renal function; 81% of subjects with GFR #15 ml/min have decreased FT3 values, 67% of them have normal TSH values; only 13% of the subjects with GFR $60 ml/min had a decrease in T3 values (p=#0.001). FT4 levels also decreased directly in relation to the lower degree of renal function (p=#0.001).Conclusions: CKD patients have a high incidence of thyroid abnormalities, low T3 syndrome is highly prevalent in subjects with GFR #15 ml/min, this is worrisome as low T3 has been associated with higher morbi-mortality in dialysis patients.

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