Malaria is one of the leading causes of morbidity and mortality reported worldwide. Malaria caused by P. Falciparum is a multisystem disorder and may have diversity of clinical presentations. We are presenting a case report of patients of Falciparum Malaria masking acute on chronic pancreatitis. We suggest that Falciparum Malaria should be included in differential diagnosis of acute pancreatitis presenting with fever especially in endemic countries.

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