Two experiments were conducted; the first one, columns on loamy and sandy soils and the second one, pots on loamy soil only for radish plants (Raphanus sativus L) to study application of nanotechnology in agricultural purposes as reducing nitrate leaching and rationalizing urea fertilizer use. The urea granules coated with 2% pomegranate peels and tea spoil powder in bulk and nanosize. Six treatments were used as follow: control (without urea U0),normal urea (U), urea coated with pomegranate peels at bulk powder (PbCU), urea coated with pomegranate peels nanopowder (PnCU), urea coated with tea spoil at bulk powder (TbCU), urea coated with tea spoil nanopowder (TnCU). The leachate was collected every 3 days up to 21 days. The results showed that a significant variation in the nitrate leaching rate at two organic residues and two sizes were applied. The highest rate of nitrate leaching obtained after three days of incubation periods for all treatments compared to other periods. The results obtained showed that U treatment had the highest rate of nitrate leaching, while PnCU treatment was the lowest rate of nitrate leaching. PnCU treatment used as best result obtained from columns experiment in pots experiment on radish plants at rates of 100 (control), 75, 50, 25 and 10% of recommended dose. The results obtained from the pots experiment showed that PnCU treatment at rate 25% urea fertilizer of recommended dose improved yield and quality of radish plants grown in loamy soil due to slow nitrogen release and reduced loss of nitrates.