A procedure is developed for the determination of Cd, Cu, Mo, Pb, Te and Ni in natural and spiked water by Atomic Absorption Spectroscopy (AAS) after preconcentration on a coniine dithiocarbamate supported by polyurethane. The sorbed elements are subsequently eluted with 5 mol L-1HNO3and the acid eluates are analysed by AAS. A 20 mL syringe served as a chromatographic preconcentration column. The sorption recoveries of elements were higher in the order of 99%. The method is also applied successfully for the determination of Cu, Cd, Mo, Pb, Te and Ni in natural and spiked water samples.
A rapid, selective and sensitive spectrophotometric method for the determination of mosarpide in either pure form or in its formulations in pharmaceutical preparations is described. The method is based on the diazotization coupling reaction of mosapride with 1-naphthol in acidic medium to give red azo dye product with theλmaxof 500 nm and is stable for more than 12 hours at optimum condition, Beer's law is obeyed at concentration of 0.2 to 12 μg mL-1at the wavelength of maximum absorbance. Common excipients used as additives in pharmaceutical preparations do not interfere in the proposed method. The developed method is highly reproducible and applied to wide variety of pharmaceutical formulation and the results were compared favourably with the reported method.
Now a days, infrastructure development holds the key for the development of every nation. Concrete is one of the most utilized material by the construction industry which is a homogeneous material prepared of heterogeneous materials like Cement, sand and aggregates. However rapid urbanization has created a huge demand for natural sand hence made it even more expensive. This led the researchers to find other materials which could be used as a replacement of sand whose main chemical composition is Silica (SiO2). After a great extent of research, researchers found that materials like Stone dust, Copper Slag, Coal Fly Ash, Carbonate Sand etc. having silica composition could be used as a replacement of sand. The Present experimental investigation is carried out for M20 grade of concrete mixes with partial replacement of Fine Aggregate (Sand) with Copper Slag. Compressive Strength and Split Tensile Strength at the ages of 7, 28 days for various combinations of Copper Slag and Sand were investigated. Sand was replaced with Copper Slag by 0%,10%, 30%, and 50%.
A fluconazole o/w microemulsion was developed for topical application using isopropyl myristate as the oil phase. Pseudo-ternary phase diagrams were constructed for the determination of existence region of micro emulsion region using the surfactant (tween 80 & Cremophor RH-40) and co-surfactant (ethanol). Different formulations were prepared for the evaluation of oil content, surfactant/co-surfactant concentration on in-vitro permeation rates. In-vitro transdermal permeability of flucanazole from the micro emulsions was evaluated using Keshary Chien diffusion cells mounted with 0.45µ with cellulose acetate membrane. The amount of drug (Fluconazole) permeated was analyzed by HPLC.
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