Building structures are subjected to vibrations due to earthquake activity. There are many characteristics that induce irregularities in buildings. Apart from other reasons, these irregularities may be; many times; due to non-uniform distribution of mass, stiffness, or strength in the structure of the building. Due to such irregularities; buildings are subjected to some undesirable effects which make them weaker compared to regular buildings. Indian Standard code of practice IS 1893 – (Part 1): 2016 [1] details guidelines to be followed so that buildings are less and less irregular. Many times such guidelines may be the result of past studies of actual performances of buildings in seismic events. It is the intended purpose of this paper to bring a review of standard guidelines which are important for irregular buildings for preventing various typical damages to occur in seismic conditions. Typical examples of past damages have been provided to draw lessons.