Alopecia areata is a clinical manifestation of baldness with the pathogenesis of an immune system disorder that damages hair follicles without scar tissue formation, characterized by the presence of round, hairless areas on the scalp. Treatment for alopecia areata includes glucocorticoids (topical, intralesional and systemic), minoxidil, anthralin, other immunosuppressive agents, and immunotherapy in severe cases. Other treatments include methotrexate (immune suppressants) and cyclosporine (calcineurin inhibitors) but their benefit may be too small and inconsistent to justify their use given their possible side effects. Currently there are only 2 drugs approved by the Food and Drug Administration to be given as alopecia drugs, namely Minoxidil and Finasterid e. Although alopecia areata is a common condition in dermatological practice, the management of this disease can be challenging because of the degree of severity and susceptibility to treatment resistance that patients can experience. This study aims to present the potential of herbal medicine as a treatment for alopecia areata. This literature review uses secondary data in the form of research journals related to the topic through PubMed, Google Scholar and Sciencedirect for a period of 5 years from 2018 to 2022. Herbal medicine has the potential as an alternative in cases of alopecia areata and can improve patient recovery.
Background: Pityriasis versicolor (PV) or tinea versicolor is a superficial fungal infection characterized by macules on the skin. It is generally caused by the fungus Malassezia. PV is found throughout the world, especially in tropical countries. Generally, this infection is influenced by humidity, hyperhidrosis, and population density around the world. One of the ways to establish PV is through the KOH examination. Purpose: Evaluating the correlation between the clinical and demographic factors and the duration of illness of outpatient PV patients of the Mycology Division of Dermatology and Venereology Department at Dr. Soetomo General Academic Hospital from 2018 to 2020. Methods: This is an observational analytic study based on medical records at the outpatient clinic of Mycology Division of the Dermatology and Venereology Department of Dr. Soetomo General Academic Hospital. The data was collected in October 2021. The chi-square test is used to analyze the data in this study. Result: 216 PV patients’ data was collected. Most gender was male, most age group was 20-60, most weight group was 51 – 60 kg, most regional origin was from Surabaya, and most duration of infection was <3 months. In this study, topical and systemic treatment of this disease had a significant relationship with patients’ duration of illness (topical p=0.05; systemic p=0.026). Conclusion: Topical and systemic treatment of this disease has a significant relationship with the duration of illness in PV patients.
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