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Objective: To establish a world-class national research network to carry out high quality obstetric ultrasound research in Ireland. Methods: A partnership of 9 leading fetal medicine physicians from 8 maternity hospitals across Ireland was formed to establish a national obstetric ultrasound research network in Ireland. A proposal was successfully submitted to the Irish Health Research Board (HRB) and a multi-million euro award was made for the establishment and operation of the network. Results: Perinatal Ireland was established through the award and comprises 8 of the leading maternal fetal medicine centres in Ireland. The network provides a collaborative partnership and research infrastructure to carry out large-scale perinatal research projects. Together these 8 centres account for over 50,000 births per annum. The infrastructure includes formalized management structures, dedicated research equipment and personnel at each site and a full-time Programme Manager. As Perinatal Ireland was the first consortium of its kind in Ireland, some difficulties were encountered during its set up. These included difficulties in recruiting sonographers due to the poor supply of trained obstetric ultrasonographers; problems with contractual arrangements regarding their employment and the need to obtain ethical approval at each of the eight sites. Hospitals without existing academic departments, where there was less of a culture of clinical research, experienced greatest difficulty in integration into the consortium and this was reflected in their recruitment performance. Hospitals where a senior clinician had substantial executive authority seemed to facilitate integration. Conclusion: A perinatal research network was successfully established in Ireland. The consortium is currently carrying out multicentre prospective research studies in ultrasound, including evaluating the role of sonographic predictors of restricted growth in twins, and expects to report initial results in 2010. Objective: To establish a consolidated web-based database linking Viewpoint ultrasound databases at 8 sites to facilitate the efficient transfer and consolidation of research data to a central, secure web-based database. Methods: Perinatal Ireland, an 8-centre research consortium, was used as a platform to develop and implement a web-based research database. The approach was 2-fold: to create an extract of ultrasound data at each centre for uploading and to set up a secure website to which data from 8 centres could be uploaded. A merge algorithm ensures all transferred study data is up-to-date and all additional study data is added when a new dataset is uploaded. The data is stored in a common database which is viewable and queryable via specific user logons for pre-authorised IP addresses. P23.10 Establishment of a web-based consolidated ultrasound database Results:The software used to record study data contains a functionality allowing the user to extract and save data to a CSV file with the aid of an SQL-like query. Once logged in the user select...

In summary a combined therapeutic approach employing local and subsequent parenteral injection of MTX with close follow up of the gradually diminishing vascularization around the chorionic sac is a reasonable therapeutic approach for the increasing number of first trimester CSPs. Determination of vascularity seems to be an important measure of healing in addition of the βhCG.Patients after Cesarean deliveries, should be encouraged to present between 6-8 weeks of a subsequent pregnancy for possible and early detection of this threatening entity. P08.02The role of ultrasound in prenatal diagnoss of the pathological invasion of placenta into the myometrium M. Kotori, F. Muhaxhiri, S. Lulaj Department of Gynecology and Obstetric, University Clinical Center, Prishtina, AlbaniaIntroduction: The placenta accreta, increta and percreta are the pathological features of the placenta insertion in myometrium. They are present in 1 : 2500 of pregnancies, in 4-10% of the cases with placenta praevia. Based on the serious obstetric complications which can appear from the pathological insertion of the placenta such as massive bleeding, hemorrhagic shock, the need for transfusion, for hysterectomy, infections, intraoperative lesions of the urinary bowel, and maternal death, this is the main need and interest of the prenatal diagnosing of this pathology. Objective: To investigate the possibility of prenatal diagnosing of this pathology with the ultrasound. Material and methods: In the study are included 84 pregnant women with the low insertion of placenta and with bleeding in the second and third trimester. They were examined with ultrasound with abdominal probe 3.5 MHz for searching of the characteristic signs of the pathological insertion of placenta in the depth of myometrium such as: the absent of the hypoehogenic retroplacentar-myometrial zone, the absent of the smooth surface with urinary bowel, the presence of the vascular lacunas (''Swiss cheese''). Results: From the 6 cases with placenta praevia accreta and increta, 5 (83.3%) were diagnosed in prenatal period with the ultrasound. Conclusions: The ultrasound examinations enable the prenatal diagnosing of the pathological invasion of the placenta in the myometrium and help us in preoperative preparation and intraoperative management.