No abstract

The preparation of substituted phthalides from or0 + I-CHOH CO CO /V^/Noh wv ch2 COThis procedure for preparing certain types of anthraquinones appeared, at first, not to be entirely general, since he was unable to reduce phthalides from opianic acid (2-carboxy-3,4-dimethoxybenzaldehyde) and phenols to the corresponding benzyl-benzoic acids. Jacobson and Adams,ld however, found that under the proper conditions these latter phthalides could be reduced, and, although the benzyl-benzoic acids could not in all cases be obtained crystalline and pure, the products served well for the preparation of anthraquinones. In this Laboratory the method has already been applied to the synthesis of morindone,16 rufiopinlg and 1 For previous articles in this field see (a) Graves with Adams,