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Madura foot is a disfiguring, disabling condition, found in the tropics and subtropics. We present a case of a farmer who presented with swelling and multiple discharging sinuses in his left foot. The offending organism, Madurella grisea was identified by fungal culture. The patient was managed with local excision combined with systemic antifungal therapy. So far, the patient has made an uneventful recovery, with no recurrences. The laboratory diagnosis proved difficult, given the limited resources. We wish to highlight the difficulties faced in diagnosis and management of this condition, as response to antifungals are dependent on the pathogen, and adherence to long term antifungals are crucial.
Burkholderia cepacia is an uncommon, multidrug resistant pathogen. We present a patient with a history of recent malignancy and uncontrolled diabetes, who presented with bacteraemia and multiple splenic abscesses due to this organism. She was managed conservatively, and made a good recovery. A high index of suspicion is required to arrive at the microbiological diagnosis and provide effective management.
We present two patients with haematological malignancies who developed skin lesions while neutropaenic and were subsequently diagnosed as having fusariosis. Although fusariosis is not as common as other fungal infections such as aspergillosis and candidiasis, it has to be considered in the diagnosis of immunocompromised patients who present with skin manifestations. Awareness of fusariosis, and early diagnosis and appropriate treatment is essential to reduce mortality.
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