The study was carried out with an aim to make a correlation between radionuclide renographyand biochemical test in the evaluation of renal diseases. A total of 275 patients with a history oflow back pain were included in the study. Radionuclide renography and biochemical test weredone in most of them in consecutive days. Among them, 241 patients were finally found to bepositive. Available USG, X-ray, IVU, TC, DC, ESR and Hb% findings were also correlated wellwith renogram. Renal diseases like renal stone, acute glomerulonephritis (AGN), ureteric stone,enal abscess, chronic renal failure, end stage renal disease (ESRD) and renal trauma wereound in most of the cases. In case of radionuclide renography, mild to severe renalnsufficiency found in 87.64% cases (single & bilateral) in contrast to biochemical test wherencreased blood urea/ serum creatinine found in 30.91% cases. Our study focuses themportance of renogram technique over biochemical test for precise evaluation of differentialrenal function.doi: 10.3329/taj.v16i2.3885TAJ December 2003; Vol.16(2): 65-67

Background: Typhoid fever is a severe debilitating and potentially life threating illness. In Bangladesh, typhoid fever is a round the year problem which sometimes take epidemic proportions. The reasons behind such occurrences are unsafe water supply, defective sewage system and unhygienic food handling practice. This study aimed to compare the efficacy of ceftriaxone and azithromycin in the treatment of uncomplicated enteric fever.Methods: An observational study was conducted at the department of pharmacology in Dhaka medical college, Dhaka, Bangladesh. Data were collected from blood culture positive patients for Salmonella typhi and Salmonella paratyphi, who admitted in the Dhaka medical college and hospital, Dhaka during the period of July 2015 to June 2016. Data was collected by using a structured questioner, face to face interview, physical examination and investigation reports. Patients were hospitalized during the entire treatment period and at admission evaluation was made by history and physical examination in a structured format. Subjects ware asked regarding changes in symptoms and possible adverse effects of the study drugs. All patients were asked to return two weeks after completion of treatment for follow up. Blood culture of Salmonella typhi or Salmonella paratyphi were done in all cases. Total 91 patients were culture positive for either S. typhi or S. paratyphi which were finally studied.Results: During the study period out of 91 patients, 51 were receiving ceftriaxone and 40 were receiving azithromycin. Clinical cure was achieved in 46 patients (90%) of ceftriaxone group and in 31 patients (78%) in the azithromycin group. There were no significant differences of clinical cure between both treatment groups (p>0.05). Mean fever clearance time in ceftriaxone group was 3±1.4 days and was 4±1.6 days for azithromycin group. Difference in fever clearance time was statistically significant (p<0.05). No clinical relapses were detected in any study subject. No major side effects of both drugs occurred in any subject.Conclusions: These results indicated that both ceftriaxone and azithromycin were effective against enteric fever caused by sensitive organisms and multi drug resistant S. typhi and S. paratyphi. It is concluded that ceftriaxone is more effective and can be a convenient alternative for the treatment of enteric fever, especially in developing countries like us where medical resources are scarce.