Cancer during pregnancy is not a common problem, but when it is detected, a serious clinical situation arises. The coexistence of a malignant neoplasm and pregnancy is a condition in which there is an ambiguous dilemma about the simultaneous development of a new life and a life-threatening disease. Ultimately, the doctor managing this patient faces two problems - the struggle for life as well the mother as the unborn child. Based on the literature studied from the MedLine database, an analytical review of cancer information during pregnancy in 2014-2018 was conducted. The pregnancy is established to be most often combined with the following oncological diseases: cervical and breast cancer (62% each), stomach and rectal cancer (11% each), ovarian cancer (5.5%). In addition, the literature describes isolated cases of lung cancer and brain tumors during pregnancy. During information processing, the late both first pregnancy, and first births it was revealed to increase the risk of cancer. Treatment of such patients should be carried out in specialized centers, and for all cases it is necessary to collect a consultation team consisting of oncologists, surgeons, obstetricians-gynecologists, radiologists, neonatologists and pediatricians. Over the past 20 years in world practice, the most preferred approach is a comprehensive start of treatment of patients without interrupting pregnancy, therefore the survival rate of both mother and fetus tends to increase.

Cervical cancer during pregnancy is the actual problem of XXI century in the gynecologic oncology. Statistics data have shown that cervical cancer takes the first place among gynecologic tumors associated with pregnancy. During the past decade a treatment plan for such patients has significantly changed in a favor of pregnancy prolonging and possibility to deliver a healthy child. We have made an informational analysis of PubMed database for 2010-2018 to assess an individual treatment of patient with diagnosed cervical cancer while prenatal screening and revealed progressive and effective therapeutic methods regarding tumor stage and gestational age. Based on learnt scientific articles and literature we have established that now the most appropriate treatment approach is managing platinum-based neoadjuvant chemotherapy to decrease a tumor size and performing opened or laparoscopic uterus-preserving surgeries during pregnancy if needed.

Over the past 10 years, the treatment of malignant gynecological tumors has changed dramatically. For many years, a radical approach - extended hysterectomy with appendages at any stage of tumor development of internal genital organs was considered to be the only correct approach. However, many young women want to preserve their fertile function, and in this regard, the treatment tactic was improved and optimized towards the development of organ-preserving methods for the treatment of gynecological cancer. Based on the literature studied from the MedLine database, an analytical review of information on the possibilities of organ-preserving treatment for gynecological cancers in 2013-2018 was prepared and the implementation of a successful integrated organ-preserving treatment was found to be available only at early stages of cervical, endometrial and ovarian cancer. The overall survival after treatment correlates with the histological structure of the tumor, the degree of its differentiation and involvement of the underlying tissues in the pathological process, as well as the volume of surgical intervention. In most cases, after an organ-preserving treatment, the risk of tumor recurrence is low, and a woman regains a chance to become pregnant and give birth to a healthy child.

In the past decade, the clinical practice of treatment of malignant gynaecological tumours has undergone cardinal changes towards introduction of organ-sparing technologies. In many respects, this is due to the fact that women want their reproductive function to be preserved. This approach is widely discussed among medical doctors and: can organ-sparing techniques influence the outcomes of treatment with respect to tumour recurrence and a woman’s reproductive potential and her ability to bear a baby. As has been found, the survival after successful comprehensive treatment of cervical, endometrial and ovarian cancer is high, and the conception and birth of a healthy child is possible in more than 50% of cases, most often with the help of assisted reproductive technologies. Key words: oncological outcomes, tumours, organ-sparing treatment, reproductive outcomes