Background and study aims: Celiac disease (CD) is a chronic systemic autoimmune disorder affecting genetically predisposed individuals, triggered and maintained by the ingestion of gluten. Triggered and maintained by the ingestion of gluten, celiac disease is a chronic systemic autoimmune disorder affecting genetically predisposed individuals. Persistent related inflammation of the duodenal mucosa causes atrophy architecture detectable on esophagogastroduodenoscopy (EGD) and histopathology. We investigated the association between endoscopic features and histopathological findings (Marsh) for duodenal mucosa in celiac disease patients and propose an endoscopic classification of severity. Patients and methods: Between January 2000 and March 2010, an electronic database containing 34,540 EDGs of patients aged > 14 years was searched for cases of CD. Out of 109 cases, 85 met the inclusion criteria: conventional EGD combined with chromoendoscopy, zoom and biopsy. EGD types 0, I and II corresponds to Marsh grades 0, 1 and 2, respectively, while EGD type III corresponds to Marsh grade 3 and 4. Results: Five patients (5.8 %) were EGD I but not Marsh grade 1; 25 patients (29.4 %) were EGD II, 4 of whom (16 %) were classified as Marsh grade 2; and 55 patients (64.7 %) were EGD III, 51 (92.7 %) of whom were classified as Marsh grades 3 and 4. The Spearman correlation coefficient (r = 0.33) revealed a significant association between the methods (P = 0.002). Conclusions: Changes in the duodenal mucosa detected on EGD were significantly and positively associated with histopathologic findings. The use of chromoendoscopy in addition to conventional EGD enhances changes in the duodenal mucosa and permits diagnosis of CD, even in routine examinations. The proposed endoscopic classification is practical and easily reproducible and provides valuable information regarding disease extension.

diagnosis about 5 years, census data used to identify male residents per birth interval were those published for the following interval (eg, 2005 estimates used for 1996e2000 births).Results From 1986 to 2000, 321 DBMD males resided in an MD STARnet site during one or more birth intervals, which produced a prevalence of 1/5000 residents. Race/ethnic-specific prevalence tended to be higher for Hispanics than non-Hispanic whites or African-Americans. Prevalence tended to be decreased for the most recent birth interval. Conclusion Our results are the first U.S. population-based report of race/ethnic-specific DBMD prevalence. Expansion of MD STARnet to two additional sites will permit computing prevalence for additional race/ethnic subgroups and birth intervals. Excess weight in childhood is a predictor of co morbidity in adulthood. This research aimed to identify factors associated with overweight among schoolchildren. This cross-sectional study involved children of both sexes aged between six and 10.9 years of age, enrolled in 24 public and private schools in the urban region of Maringá, Paraná, southern Brazil. The collection were done in the school environment, with measurement of the weight and height defined by calculating the Body Mass Index (Cole et al 2000; 2007). The socioeconomic status of families was considered the guidelines of ABEP (2008). For the statistical analysis it was used the variance analysis model and the c 2 test, considering p<0.05. The total evaluation of variables was done getting adjusted to a model of Multinomial Logistic Regression considering the nutritional condition as response variable and the age, gender, socioeconomic status and Body Mass Index as explanatory variables. This project was approved by the Permanent Ethic Committee of Researches involving human beings from UEM. From 5037 schoolchildren, 53.2% were female, age range 8.761.3 years old and 24.1% presented excess weight. Overweight children from private schools and better socio-economic conditions showed positive relation with the excess weight (p<0.001) and children younger than 8 years old have more chances of being overweight (p¼0.038). The impact of these results accelerates the urgency of preventive actions towards overweight and its intercorrences in precoce ages. Introduction Previous studies have shown that Green tea consumption reduces colon cancer mortality and the risk of liver cancer. However, no studies have examined the association between green tea consumption and all-cancer mortality. Methods A multi-centre population based prospective cohort study in 12 districts in Japan collected baseline data on 12 490 participants from 1992 to 1995. Individuals for whom a history of green team consumption was missing were excluded as were individuals with a past history of any cancer, myocardial infarction and stroke. Green tea consumption was measured using self-report questionnaires. Date and cause of death were determined by death certificates review. Data were analysed using Cox proportional hazards modelling....