The urolithiasis is a very common disease that it causes, in addition to the suffering for the patients, an important cost sanitary partner. The composition of the renal stones that can influence in the treatment and later evaluation of the disease, varies in the different zones. In our work the composition of the renal stones received in the Biochemistry department of the H.C.U of Zaragoza studies during year 2002, with a brief approach to the epidemiology of the disease in the Area III of Zaragoza. The rate of incidence was of 0.35% with a clear predominance in men; the most frequent renal stones were those of pure calcium oxalate or calcium oxalate combined with apatite carbonate, although the percentage of samples gathered with respect to the total of diagnoses as soon as it surpassed 10%. Not found significant differences between the composition of the renal stones coming from the different zones from our Area, nor based on the sex of the patients. Given the influence of the composition of the urolithiasis for its treatment, we must insist on the collection of the greater number of samples for its analysis, although the epidemiologic data and the study of the urinary sediment can be used in the practice.
We highlight the importance of evaluation of the ESS, based on its results. nMM due to S. pneumoniae represent an important group of diseases and their case fatality is high. The completeness of the ESS in Saragossa was over 80% when the mandatory reporting system and the MBDS were combined. Incorporating the MBDS into surveillance would facilitate the estimation of the real incidence of various diseases subject to mandatory reporting.
Posible relación entre alopecia areata e infecciones por enterovirus Introducción: la alopecia areata es una enfermedad autoinmune de etiología desconocida que se asocia a otras enfermedades autoinmunes. La enfermedad mano-pie-boca es una infección viral frecuente en la edad pediátrica, causada por diferentes serotipos de enterovirus y que en ocasiones asocia onicomadesis. El presente estudio pretende comprobar un incremento de los casos de alopecia areata tras un brote de enfermedad mano-pie-boca en nuestro entorno. Material y métodos: identificación de los pacientes menores de 14 años diagnosticados de enfermedadmano-pie-boca y/o alopecia areata en un área de salud entre el 1 de enero de 2011 y el 31 de diciembre de 2012. Revisión de historias clínicas, recogiendo fecha de nacimiento y diagnóstico, edad al diagnóstico y características clínicas. Resultados: se encontraron 49 pacientes diagnosticados de enfermedad mano-pie-boca y siete diagnosticados de alopecia areata. Se confirmó un brote de enfermedad mano-pie-boca con 42 casos en un periodo de ocho semanas. Se observó un incremento posterior de los casos de alopecia areata (cuatro casos en las cuatro semanas siguientes, frente a tres casos a lo largo de los 11 meses previos y ninguno durante el año anterior). Conclusiones: tras un brote de enfermedad mano-pie-boca se observó un incremento del número de casos de alopecia areata. Este hecho, unido a la asociación de la alopecia areata con otras enfermedades autoinmunes y a la relación encontrada entre infecciones por enterovirus y procesos autoinmunes como la diabetes mellitus tipo 1, plantea una posible relación causal entre infecciones por enterovirus y alopecia areata, así como un posible componente de autoinmunidad en la onicomadesis asociada a la enfermedad mano-pie-boca.
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