No abstract

In the present study, a series of thiodihydropyrimidine derivatives were synthesized from different substituted aromatic aldehydes, ethyl acetoacetate, and urea/thiourea using a bimetallic TUD‐1 catalyst. The structures of all the synthesized compounds were characterized by melting point determination, thin layer chromatography (TLC), infrared (IR), 1HNMR, and 13C‐NMR values. All the synthesized compounds were screened for their antimicrobial activities against two gram positive bacteria, two‐gram negative bacteria, and two fungal strains.