Today most adolescents have their first sexual experience at the age of 15–19. However, only 44% of girls and young women (15–24 years old) report about contraception at that moment. A decision on pregnancy in adolescence is a difficult choice and any scenario may cause serious medical and social problems. Complications after an artificial abortion have a negative impact on a woman’s fertility. Diabetes mellitus type 1 and arterial hypertension accompanied with obesity within the metabolic syndrome are defined by the World Health Organization (WHO) as diseases, which increase risk of an unplanned pregnancy. The article consoders problems of interaction of a doctor and a teenage girl with endocrinopathy, when discussing her sexual health, the analysis of the literature reflecting the influence of contraception on the course of the underlying pathology is presented. The authors formed a list of drugs acceptable for use in diabetes and obesity based on assessment of risks and preferences from the use of different methods of fertility control. The work contains information about the procedure of starting contraception, the rules of future dynamic monitoring of the patient.

Autonomous cardiac neuropathy is a diabetic complication characterized by early disseminated sympathetic and parasympathetic small-fiber neuronaldegeneration. Prevalence, pathogenesis, risk factors, clinical manifestations, and early diagnosis of pathology are discussed.

A clinical observation of a patient with Swyer's syndrome is presented. The article presents anamnesis data, phenotypic signs, clinical symptoms and objective data of the patient, the results of instrumental and hormonal studies, on the basis of which doctors of different specialties may suspect a violation of sex formation with XY gonadal dysgenesis.

MEHMO syndrome (OMIM: 300148; ORPHA: 85282) is a disease appears by mental retardation, epilepsy seizures, hypogonadism, microcephaly, and obesity. Pathology is associated with mutations in the EIF2S3 gene located on the X chromosome and leads usually to serious disability of patients. The article presents a clinical observation of the case of the syndrome in two male cousins with microcephaly, manifested by a complex of endocrinopathies (hyperinsulinemic hypoglycemia, multiple adenohypophysis hormone deficiency) and accompanied by severe neurological abnormalities (epilepsy, spastic tetraparesis, optic nerve atrophy). The complexity of the diagnostic due to the rarity of this syndrome, is described.

May 14, 2014 marks 200 years since the establishment of the Medical Department of the Imperial Kazan University (now Kazan State Medical University, KSMU). Since the XIX century, scientists of the Kazan Medical School studied physiology and pathology of the endocrine system. The first researchers were interested in the problems of endemic goitre, diabetes mellitus, and function of the adrenal glands. In 1976, the Endocrinology Department was organised in the Kazan State Medical Institute, the first among universities of the RSFSR. The head of the Department, V.V. Talantov, became the chief non-staff endocrinologist of the Ministry of Health of the Republic of Tatarstan (RT) and organiser of the Association of Endocrinologists in the RT. Moreover, he contributed to the organisation of the endocrine service in the republic and endocrinology began to be taught as an independent discipline. V.V. Talantov was a member of the Scientific Council of Endocrinology of the Russian Academy of Medical Sciences, Deputy Chairman of the Committee of Endocrinology Problems of the Ministry of Health, and a member of the editorial boards of four medical journals. The research in the field of endocrinology is now actively continued on the endocrinology course at KSMU. In-depth study of various aspects of the pathogenesis of diabetes and its complications was selected as the first-priority.