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Tuberculosis is a global pandemic accounting for 9.2 million new cases and approximately 2 million deaths annually. Tuberculomata of the brain are a common feature of Intracranial tuberculosis. In the past the diagnosis was based on the evidence of active tuberculosis, elsewhere in the body, characteristic Cerebrospinal fluid (CSF) findings, a biopsy of necropsy. CSF findings would be equivocal in the absence of meningeal involvement. In India, its incidence is 12 to 30% of all intra-cranial space occupying lesions. The material consisted of 1000 patients who were admitted during the two year period, presenting with clinical features of headache vomiting, or focal/generalized seizures. These patients belonged to the acute medical care unit and pediatric Medical Units of a tertiary care hospiatl in South India. This study is a retrospective one and only those cases who had their Computerized Tomography (CT) scan of head and brain done were included. A total of 276 patients with definite CT findings of tuberculoma were analyzed for their age, and sex incidence, numbers, size and site of correlated with the clinical presenting features, duration of illness, CT morphology. A definite pattern of CT morphology of tuberculomata was seen, small sized lesions were the commonest 61 % , medium size lesions 30 % large size lesions 9 % . Shape: Ring and disc lesions 79 % irregular ball like nodular lesions 21 %. Number: Single lesions were the most frequent 86 % though multiple lesions were encountered in 14 % cases of our study. Site: Supratentorial involvement we noted in 96 % of patients and only 4 % infratentorial involvement was seen. The commonest site of supratentorial involvement of brain by tuberculoma was the parietal lobes. The advent of CT has definitely helped in the early diagnosis of intracranial tuberculomata. It is cost effective and currently available even at the district headquarter level, and is therefore effective in isolating tuberculomata cases from other intracranial space occupying lesions by its typical CT morphology unsuspected cases are coming to light who and are amenable to medical treatment if diagnosed at the earliest by the help of CT.

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