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Aim - study of renal arteries denervation for the surgical treatment of primary arterial hypertension. Materials and methods. Radio-frequency ablation from the side of artery adventitia was carried out on preparations of the renal arteries. Results. The study determined comprehensible regimes of radio-frequency ablation, not resulting in a large degradation of the renal arteries strength properties, but providing reliable denervation of these arteries. Micro-photos of the renal artery wall after carrying out radio-frequency ablation were obtained. Conclusion. It is shown that the most comprehensible way of the renal arteries denervation is radio-frequency ablation from the side of artery adventitia.