The article reflects the results of the work of the psychiatric and psychotherapy services of the Hospital for war veterans converted into an infectious hospital in the context of the new coronavirus infection (COVID-19) pandemic. The aim of our study was to determine the frequency and nature of mental disorders in patients treated in hospital for a new coronavirus infection (COVID-19) between April and June 2020. The case histories of patients who received psychotherapy or psychiatric care in addition to the treatment of the underlying disease were studied retrospectively. The study included 557 patients, 266 men, 291 women, the average age was 62.36+18.65 years. The work used clinical and psychological methods using the international classification of diseases 10 revision (ICD-10), the diagnosis of a new coronavirus infection (COVID — 19) was carried out in accordance with the Temporary guidelines of the Ministry of health of the Russian Federation. As a result of data evaluation, it was revealed that the proportion of patients requiring consultation or treatment by a psychiatrist or psychotherapist was 557 (7,10%) patients of the total number of hospital admissions, of which emergency psychiatric care was indicated in 58 (10,41%) of cases. The transition of the hospital to an infectious diseases hospital mode has set new challenges for the psychiatric and psychotherapy service, which required organizational measures, therapeutic issues and confirmed the need for participation of mental health specialists in providing full-fledged medical care in the treatment of somatic disorders.

The aim of the study was to investigate the structure of delirium in elderly patients with different outcomes of coronavirus infection.Materials and Methods. The study was carried out on the basis of Hospital for War Veterans, St. Petersburg. The study involved  30 patients: 13 male and 17 female (median age (Med) 70.5, interquartile range (IQR) 62-83) with clinical diagnosis: "New coronavirus infection COVID-19 (PCR+), F05.86 other delirium in association with other viral and bacterial neuroinfections. Peculiarities of delirium manifestations were studied using Delirium Rating Scale-Revised-98 (DRS-R-98). Current physical condition was monitored using The National Early Warning Score (NEWS2) for COVID-19.Results: All patients had moderate to severe disorders of the wake-sleep cycle on the DRS-R-98 scale. In addition, perceptual and long-term memory impairments were common. A significant correlation (p<0.05) was found between the severity of the physical condition and disorders of the sleep-wake cycle, lability of affect, formal thought disorders, motor agitation, and disorientation. In addition, there were significant correlations (p<0.05) between delirium symptoms and physical status scores on the NEWS2 scale. In lethal patients, more pronounced disturbances were recorded on sleep-wake indicators (Med.3.0, IQR 2.0-3.0 vs Med.2.0, IQR 2.0-3.0, p=0.0327) and motor agitation (Med.2.0, IQR 1.0-2.5 vs Med.1.0, IQR 0.0-2.0, p=0.441). A logit regression model showed that the variables "respiratory rate," "heart rate," and the final NEWS2 score could be considered predictors of disease outcome.Conclusion. Delirium, one of the most frequent manifestations of acute brain dysfunction, is a serious complication of COID-19 in hospitalized patients and a strong predictor of adverse outcome of coronavirus infection in older patients.

Objective: to analyze clinical and follow-up indicators in patients with mental disorders and COVID-19 and to identify on their basis predictors of poor outcomes associated with mental state.Patients and methods. We conducted a prospective study in a multidisciplinary hospital. The severity of coronavirus infection was determined according to the temporary guidelines. Data collection was carried out using a patient chart consisting of 109 variables. Predictors of poor outcomes were determined using predictive models (logit regression, Cox model). The study included 97 patients: 41 men (42.3%) and 56 (57.7%) women, mean age – 62.3±15.3 years. 26 patients died; 71 patients recovered.Results and discussion. The death occurred on 11.5 day. The mental state of these patients was severe, with a predominance of delirium cases. With increasing age, the probability of non-lethal outcome decreases [hazard ratio (HR) 1.03; 95% confidence interval (CI) 1.00–1.06; p=0.037]. The risk of death increased by 1.03 (p=0.037) for each year of life. An improvement in the mental state of patients during psychotropic therapy is associated with an 11.11-fold decrease in the risk of poor outcome of coronavirus infection (HR 0.09; 95% CI 0.01–0.76; p=0.027). Delirium is a predictor of low patient survival, especially in prolonged hospitalizations (HR 4.55; 95% CI 1.66–12.48; p=0.003). The severity of coronavirus infection makes the greatest contribution to the poor outcome: the risk of death increases by 33.17 times (CR 33.17; 95% CI 4.01–274.65; p<0.001). The severity of the mental disorder had a greater impact on the risk of death compared with age, increasing it by 4.55 times (p=0.003).Conclusion. We found significant differences between the groups of deceased and surviving patients with COVID-19 concerning the variables related to certain mental disorders, their severity and dynamics, and the severity of coronavirus infection. In addition, the age of the patients had a significant impact on the prognosis of COVID-19. The results reflect the special prognostic significance of delirium in the structure of mental disorders developing in patients with coronavirus infection.

Introduction. COVID-19 affects not only the respiratory tract and lungs, but also the central nervous system. These organic lesions lead to the development of mental and neurological disorders. The structure of psychiatric disorders in COVID-19 is poorly understood, but the data are important for the management and planning of medical care. The purpose of the study. Analysis of the management of psychiatric care in a multidisciplinary hospital from the point of view of the algorithmization of the work of a psychiatrist and psychotherapist in the context of COVID-19. Material and methods. The relevant materials on the results of the activities of the psychiatric service of the hospital for war veterans in St. Petersburg during the coronavirus pandemic were analyzed. Results. Psychiatric and psychotherapeutic care was provided to COVID-19 patients or suspected of having the disease admitted to the hospital. As a result of a psychiatric examination, the observation mode was determined in the admissions department, the intensive care unit and the infectious diseases department. Indications for the provision of psychiatric and psychotherapeutic care and transfer to a psychiatric hospital with departments for patients with coronavirus infection have been developed. Limitations of the study. The results of this study cannot be extrapolated to the work of all multidisciplinary hospitals, because associated with the presence of a psychiatrist and a psychotherapist in the staff of the institution. A limitation can be considered the non-inclusion in the study of persons under 45 years of age. Conclusion. The experience of the psychiatric service of a multidisciplinary hospital reflects the need for the activity of the psychosomatic link in the context of the COVID-19 pandemic.

Introduction Clinical practice has shown that SARS-CoV-2 viral infection increases the likelihood of developing mental disorders.Clinical practice has shown that SARS-CoV-2 viral infection increases the likelihood of developing mental disorders. Objectives To analyze clinical indicators of patients with COVID-19 with mental disorders and to identify predictors of adverse outcomes associated with mental state on its basis. Methods The study included 97 patients, 41 men and 56 women (62.3±15.3 years of age). During the observation period, 26 people died and 71 people recovered. Data collection was carried out using a questionnaire (109 variables). Binary logistic regression and Cox proportional hazards regression were used. Results In the study group, death occurred on average after 11.5 days. In this group, the mental state of patients was more severe with a predominance of cases of delirium. With age, the probability of a fatal outcome increased by 1.03 with each year of life. The severity of mental disorder had a greater impact on the risk of death compared to age (p=0.003). Improvement of the mental state of patients during psychotropic therapy was associated with a reduction in the risk of an unfavorable outcome of coronavirus infection by 11.11 times. The greatest contribution to the unfavorable outcome was made by the severity of infection: the risk of death increased by 33.17 times. Conclusions A severe or extremely severe mental state increased the risk of death by 4.55 times. The most significant factor in predicting mortality was associated with the severity of the underlying disease. Disclosure No significant relationships.