Delegates of the 2022 Symposium on Dementia and Brain Aging in Low-and Middle-Income Countries, representing over 40 countries, met in Nairobi, Kenya, December 5-9 to highlight advances in dementia prevention, diagnosis, care, and research, as well as explore the future needs of the global community.Dementia poses a major threat to optimal brain health and remains a priority for the demographically ever-changing worldwide population.It incurs substantial individual, societal, and global costs. By 2030, the majority of the 78 million people with dementia will be living in low-and middle-income countries (LMICs). Upon consideration of these grave statistics and new diagnostic paradigms with available prevention and treatment strategies, we, the undersigned delegates of the symposium, including the Organizing Committee and speakers, and the African Dementia Consortium (AfDC), with frontline and lived experience, call upon the global community, including governments, policymakers, international economic forums, health and social care providers, together with private and public research funding agencies, researchfocused organizations such as universities, nongovernmental organizations, and technology and pharmaceutical companies, to act as follows: