No abstract

Direct visual internal urethrotomy (DVIU) is the most commonly performed procedure for bulbar urethral stricture disease of length 10mm or less. DVIU alone, classically, has a poor long-term success rate. The objective of this prospective study conducted at VIMS Bellary from Sep 2012 to Aug 2013 is to compare the effect of submucosal injection of mitomycin-C after DVIU on recurrence rate of bulbar urethral stricture with DVIU alone. MATERIALS AND METHODS: Forty five male patients with bulbar urethral strictures of 10mm or less were included in the study with every alternate patient undergoing DVIU was injected urethral submucosal Mitomycin-C(0.1mg) at the urethrotomy site. Mitomycin C injected in 23 patients. Mean stricture length, as measured by retrograde urethrography (RUG) was 0.75 cm. Mean preoperative uroflow was 10.5ml/sec. The patients were re-evaluated after 6 months and 1 year by uroflow, USG abdomen and RGU, and the stricture recurrence rate was compared between the two groups. RESULTS: Analysis of the results revealed a stricture recurrence rate of 47% in the DVIU only group while the recurrence rate in the Mitomycin C group was only 13%. This difference was statistically significant. The mean uroflow of the recurrences in the Mitomycin C group was 13 ml/sec,and DVIU group 11.75 ml/sec. CONCLUSIONS: Submucosal injection of Mitomycin C after DVIU is effective in reducing the rate of early recurrence in our short term follow up study.However further studies are required to know the long term results. In our study aetiology of stricture has no relation to the recurrence rate after DVIU.

Primary tuberculosis of penis is very rare and we present a case report of it presenting as ulcer over the glans. Biopsy and histopathological examination confirmed the diagnosis and patient responded well for antitubercular treatment. Sexual partner evaluation turned out to be having genital tuberculosis and possibility of spread through sexual contact is strongly considered. Rarity of the clinical case is emphasized here.

INTRODUCTION:Routinely we insert stent after Ureteroscopic lithotripsy, can silodosin be used instead of stent after ureteroscopic lithotripsy in order to avoid stent related morbidity. OBJECTIVE: This study compares efficacy of silodosin with stent to prevent stent related morbidity in post URSL patients. MATERIALS AND METHODS: From August 2013 to July 2014, 40 consecutive patients with 5 to 18 mm ureteral stones undergoing URS using pneumatic lithotripsy were alternatively grouped into each group. Group 1 (20 patients) stent removed after 2 week, and group 2 (20 patients) silodosin 8mg given daily night for 2weeks. After discharge patients were asked to report either immediately if they develop flank pain and fever or on post-operative day 3, 7, and 15. RESULTS: The two groups were comparable in relation with the duration of stent and silodosin therapy, 3 out of 20 patients in whom silodosin was given had flank pain which subsided with analgesics. CONCLUSION: This study demonstrates that silodosin can be used safely instead of stent in an uncomplicated URSL but, needs large scale multicentric randomized control trails. KEYWORDS: Silodosin, Stent, Post URSL. INTRODUCTION:Routinely we insert stent after Ureteroscopic lithotripsy as the placement of a Double-J stent helps to avoid the complications of pain and infection that can result from ureteral edema.But Stenting can cause discomfort 1,2 to the patients, presence of intraureteral stent carries risk of bacterial colonization and subsequent urinary tract infection 3 and encrustation. 4 In addition to these, presence of intraureteral stents induces vesico-ureteral reflux specifically with high bladder pressure during voiding, 5 and there is need for stent removal as an additional procedure.Silodosin is a selective α-1 receptor (1A, 1B, 1D) antagonist with documented use in urology in the management of LUTS in BPH 6 and also in spontaneous expulsion of distal ureteric stones 7 .So we wanted to know if silodosin can be used instead of stenting to serve the same purpose.