Background: Gestational trophoblastic disease refers to the heterogeneous group of interrelated lesions that arises from abnormal proliferation of placental trophoblasts. GTNs are among the rare human tumours that can be cured even in the presence of widespread dissemination. Although GTNs commonly follow a molar pregnancy, they can occur after any gestational event, including induced or spontaneous abortion, ectopic pregnancy, or term pregnancy. The study was conducted to know the incidence of different types of gestational trophoblastic diseases in the local population and the percentage of people ultimately requiring chemotherapy.Methods: The retrospective analysis of case record of 124 women with a diagnosis of GTD admitted to Karnataka Institute of Medical Sciences Hubli between November 2008 to November 2017.Results: A total of 124 cases of GTD were reviewed. Hydatidiform mole was diagnosed in 91 patients; of those experienced spontaneous remission after evacuation. 04 patients had persistent gestational trophoblastic Neoplasia and 13 cases of invasive mole (GTN) 1 case of epitheloid trophoblastic tumors and 15 cases of choriocarcinoma 99 (80%) had low-risk GTN, 25 (20%) had high-risk GTN.Conclusions: Hydatidiform mole was found to be the most common form of gestational trophoblastic diseases. Majority of the cases got cured by simple surgical evacuation. During the course of our study some rare cases of gestational trophoblastic diseases were noted. Patients’ compliance for serial follow up is a highly challenging task in developing countries. Registration of women with GTD represents a minimum standard of care.
Background: The study was aimed to evaluate the effects of combined spinal epidural analgesia on the duration and outcome of labour in nulliparous parturients in comparison with parturients not receiving any analgesia.Methods: It is a prospective clinical study. The present study was carried out in the labour ward, KIMS Hubli. Nulliparous parturients in early active labour were divided into two groups. CSE group (n=40) and non CSE group. In present study CSE was performed with intrathecal 1.25mg of levobupivacaine with 25mcg fentanyl initially and this was followed by epidural boluses of 10ml of 0.0625% Levobupivacaine with 2mcg/ml fentanyl through the epidural catheter whenever the patients’ pain score is more than 4.Results: Mean duration of active labour was 139+/-41.2min in CSE group and 251.1+/-57.9 min in non CSE group. The rate of cervical dilatation was 2.63+/-0.66cm/hr. in CSE group as compared to 1.45+/-0.38cm/hr in non CSE group. The duration of second stage of labour was similar in both groups. The spontaneous vaginal deliveries was77.5% in CSE group as compared to 79.5% in non CSE group. Assisted vaginal deliveries were 15% in combined spinal epidural analgesia group compared to 10.3% in non CSE group which was statistically insignificant. LSCS was 7.5% in control CSE group compared to 10.3% in non CSE group. Maternal satisfaction was excellent in majority of parturients in CSE group. The perinatal outcome was not affected in CSE group. The incidence of complications were very minimal in present study.Conclusions: Authors concluded that combined spinal epidural analgesia provides safe and excellent analgesia with no significant increase in the caesarean section and instrumental delivery rates. In addition, CSE decreases the duration of first stage of labour with no effect on perinatal outcome.
The aim was to create awareness of chickenpox among parents and guardians of children attending pedodontic OPD. Objectives: To create awareness of etiology, signs & symptoms, treatment and prevention about chickenpox among parents and guardians of children attending pedodontic OPD. Background: Chickenpox is a common childhood illness especially in kids under age 12. Caused by the varicella-zoster virus (VZV), chickenpox is very contagious. Kids who do get it might have an itchy rash of spots all over the body and flu-like symptoms. An infected child should stay home and rest until the rash is gone. Varicella vaccine is given when kids are between 12 and 15 months old, followed by a booster shot at 4 to 6 years of age Reason: Chickenpox is a rapidly spreading contagious disease among children which spreads both through air and direct contact, hence it is essential to beware of it. Methodology: Data was collected among 50 parents or guardians of children attending pedodontic OPD, using a questionnaire that contained 25 questions.
Conclusion:Chickenpox is a contagious disease recognized by a characteristic and often pathognomonic maculopapular vesicular rash. Varicella may lead to serious complications, including secondary bacterial skin and soft-tissue infections, cerebellitis, encephalitis, pneumonia, and coagulopathy. Neonates, adolescents, and immunocompromised individuals are more susceptible to complications. The study concludes that majority of the people have general knowledge about treatment, prevention and specific knowledge about the chickenpox disease.
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