Essential oils are being used to improve health due to their high nutritive value. In this study, the comparative effects of Sesame oil and Clove oil were assessed on growth performance, blood profile and immunity of male rabbits. A total of 108 male rabbits were divided into 3 treatment groups; Treatment group A (Sesame oil), Treatment group B (Clove oil), Treatment group C (Sesame oil + Clove oil). Each treatment group was further divided into 4 subgroups according to dosage design of oils. The control group was untreated, while treatment dose for groups A and B was divided into 3 different concentrations; 0.1, 0.2 and 0.3ml/kilogram Body Weight. Whereas, the treatment concentrations for group C were as; 0.1+0.1, 0.2+0.2 and 0.3+0.3ml/kilogram Body Weight of oils for 1-1.5kg of rabbits. The rabbits were managed in proper caging under controlled conditions of photoperiod (12 light: 12 dark cycles) 23±2ºC of temperature. The selected dose concentration of each oil was administered orally and once a day for six weeks. The results showed that both oils had significantly enhanced the growth performance and reduced the Feed Conversion Ratio. The hematological parameters were increased in all treatment groups, respectively. The Enzyme-linked Immunosorbent Assay for Rabbit Hemorrhagic Disease Virus also showed a significant increase in antibody titer level. The study showed that Sesame oil and Clove oil as dietary supplements have significantly (p<0.05) improved overall performance of male rabbits. The current study clearly indicated that both oils could be a better choices for health purposes.