Predicting the onset of pregnancy by in vitro fertilization (IVF) in women with tuboperitoneal infertility is a pressing challenge of modern medicine. Aim: to develop a method for determining the chance of pregnancy by IVF in women with tuboperitoneal infertility, based on the analysis of physiological parameters, using the binary logistic regression. Materials and methods. The object of the study is clinically healthy women before pregnancy and in the first trimester after conception, women with tuboperitoneal infertility before entering the IVF and in the first trimester of gestation, and women with tuboperitoneal infertility and an unsuccessful IVF trial. We analyzed the state of the cardiovascular system and autonomic regulation, adaptive capabilities and height-weight indicators at the first stage of the study. The data were statistically processed using the Microsoft Office and Statistica10 software package. We used the binary logistic regression method to create a model for predicting pregnancy in the second stage. Results. Based on the physiological indicators obtained using logistic regression analysis a mathematical model was built – a formula for assessing the probability of non-pregnancy. Conclusion. The quality of prognosis of the binary logistic regression model was 97.2%. The model can serve as a method for predicting the onset of pregnancy by IVF in women with tuboperitoneal infertility. We recommend this method for use in the work of a practicing physician.

Aim. The objective is to explore the incidence rate and the specifics of the clinical course of herpesviral meningitis in children and adults. Materials and methods. The post-hoc analysis of 23 patients’ records has been carried out. The patients were admitted to State Budgetary Healthcare Institution of the Tyumen Region, Clinical Hospital for Infectious Diseases, City of Tyumen, during the period of 2018-2019 diagnosed with meningitis of herpesviral etiology. When analysing the data the following aspects were taken into account: age, sex, etiological agent, complaints at admission, results of clinical examination and laboratory findings. Results. Twenty-three (23) cases of herpesviral meningitis were registered during the period of two (2) years; mixed infection was detected in every fifth patient. Epstein Barr viral meningitis was diagnosed in most cases and was detected 3.5 times oftener in adults than in children. Herpes Simplex Virus meningitis was the second one in terms of detection rate and it affected only adults. Varicella Zoster Virus meningitis was detected two times rarer than Herpes Simplex Virus and only in adults. The herpesviral meningitis caused by human herpes virus type 6 was detected with the same rate as Varicella Zoster meningitis but was registered among children only. Cytomegaloviral meningitis was detected in one adult who was affected by severe immune deficiency. Conclusion. The detected specifics of the incidence of the herpesviral meningitis with respect to a patient’s age will enable a practitioner to suggest the possible meningitis etiology and to prescribe appropriate treatment thus improving the prognosis for the disease.