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In previous studies it was found that the growth of 110 of 169 strains of bacteria tested was prevented by human saliva (Bibby, Clough and Hine, 1938). This effect was more marked against some types of organisms than against others, those most affected being bacilli and cocci isolated from air and water; those least affected, organisms isolated from the mouth. Differences occurred in the inhibitory potency of saliva from individual to individual and from time to time. Dissimilarities were noted between the agent effective against Micrococcus lysodeikticus and that acting on strains of lactobacilli, streptococci, and staphylococci. The former activity was removed by Berkefeld-N filtra

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