Oral leukoplakia (OL) is one of the most common potentially malignant disorder of the oral cavity (van der Waal, 2009). It was recently defined by a WHO collaborative centre as "white plaque with a questionable risk of malignancy once all other similar clinical lesions that carry no increased risk of cancer have been excluded" (Warnakulasuriya et al., 2021). It has an estimated prevalence of 4.11% (95% CI = 1. 98-6.97;Mello et al., 2018); an annual risk of malignant transformation of between approximately 2% and 3% (Carrard & van der Waal, 2018) and the pooled proportion of malignant transformation is 9.8% (95% CI: 7.9-11.7), according to a systematic review covering the last 5 years (Aguirre-Urizar et al., 2021).When treating OL, it is important to firstly eliminate any possible etiological factors, such as tobacco or alcohol consumption. If the lesion cannot be related to any of the above, or if it persists for longer than 3 months after the aforementioned factors have been eliminated, a biopsy must be taken in order to confirm the diagnosis