Scanning electron microscopy is commonly used to study the normal or pathologically altered cochlear epithelium. It is especially useful for the study of ototoxicity in humans or animals. A cochlear microdissection technique in the guinea pig is presented which permits examination of the whole membranous cochlea with little artefactual damage to the sensory structures under study.
Head and neck surgery may be complicated by penetration of the dura resulting in meningitis, cerebrospinal rhinorrhoea, cerebral abscess or other intracranial complications. The strength of the dura mater both protects the brain and spinal cord and makes dura an ideal material for grafting (when needed). This study examines the thickness and histological composition of dura mater at various sites encountered in head and neck surgery. Dura was removed from eight specified locations in 14 adult cadavers. Microscopically, this dura was found to consist predominantly of collagen fibres, although the thickness of the dura varied between sites. Dura was significantly thinner in relation to the ethmoid sinus (P less than 0.01), tegmen (P less than 0.05) and sigmoid sinus (P less than 0.001), indicating its greater susceptibility to possible injury at these sites during surgery. The variety of its thickness also makes dura a more versatile homograft material than hitherto realised.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.