Toxic epidermal necrolysis (TEN) is a rare condition that was described by Lyell in 1956. It is a severe, acute, adverse, primarily drug‐induced, potentially fatal, cutaneous reaction that is characterized by large areas of skin desquamation and sloughing, similar in many aspects to second‐degree burns. The treatment of cutaneous drug reactions rests essentially on immediate diagnosis and recognition of the disease process, accurate history, thorough physical examination, prompt discontinuation of the offending drug, and supportive care. TEN patients are best managed in specialized burn units. Nevertheless, the management remains very much individualized, based on the clinical setting. Topical wound care remains an essential factor in the treatment of burn‐like syndromes and is a main determining parameter for morbidity and mortality. As the value of moist environment in wound healing is being fully appreciated, we report on the use of a newly introduced ointment, the Moist Exposed Burn Ointment (Julphar; Gulf Pharmaceutical industries, Ras El‐Khaymah, United Arab of Emirutes), a moisture‐retentive ointment, in the successful management of a case of TEN.

Plexiform schwannoma is a rare neurogenic tumor, arising from skin and subcutaneous tissue. The presence of multiple schwannomas suggests a possible association with neurofibromatosis type 2 (NF2). A 50-year old male patient presented with multiple papulo-nodular cutaneous lesions on both arms and forearms. Histopathological examination revealed a dermal multinodular pattern of well-circumscribed masses of closely packed cells, with peripheral myxoid tissue, well-encapsulated in a thin collagenous capsule. S-100 immunohistochemical staining was diffusely and strongly positive. Neuron-specific enolase was positive, confirming a neural tissue tumor. An audiogram and Magnetic Resonance Imaging (MRI) of cerebro-pontine angle showed no detected abnormality, excluding acoustic neuroma. Thus, we present a case of multiple bilateral isolated cutaneous plexiform schwannomas, not associated with NF2. Multiple plexiform schwannomas is a very rare entity, distinct from neurofibromatosis (NF), and being confined to the dermis is even more rarely reported.

Background: Hypertrophic scars and keloids can be described as variations of typical wound healing. Aim of this study was to find out the dermoscopic differentiating features between keloids and hypertrophic scars in their recent phases of development in Egyptian population. Patients and Methods: An observational cross-sectional design of 30 cases that assigned according to histopathological analysis into two groups; Keloids and Hypertrophic scars. Then the polarized non-contact mode of a Dermlite© DL3 "Gen, USA" at a magnification of 10 × was used to capture dermoscopic images for both groups. The surface morphology and the dermoscopic criteria were recorded directly from the patients and included vascular structures (Arborizing, linear and comma shaped vessels), erythematous or white patches. Results: Statistical analysis revealed that patients with keloids are more likely to be associated with the presence vascular structures on dermatoscopy. The analysis of types of vascular structures showed that arborizing vessels, in particular, were significantly related to keloids. In contrast, the dominant dermoscopic feature in Hypertrophic scarring was the presence of scarring as presented in the form of erythematous or white patches with scanty or absent vascularization. Conclusions: Dermatoscopy should be considered as a routine investigation of any case with abnormal scarring for a better differentiation between keloids and hypertrophic scars, and hence a better evaluation and treatment of each type.

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