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In this study, we consider the features of the deep structure of the Earth’s crust and the lithospheric mantle in the central part of the Lower Amur mineragenic zone and in the area that flanks on the zone from the west, including the Albazinsky gold ore cluster. Zones with a sharp change in density and magnetic properties associated with Late Cretaceous-Early Paleogene magmatism were established based on the calculated density and magnetic depth models of the territory. A ring structure ~200 km across was identified, which is characterized by the low-density lithospheric mantle and density and magnetic inhomogeneities in the Earth’s crust associated with a wide development of intrusive bodies within it, as well as their attitude and composition. The spatial relation of gold ore districts, clusters and deposits to density and magnetic inhomogeneities in the crust and lithospheric mantle is analyzed and the main patterns in their occurrence are shown. As a rule, they are confined to the low-density zones in the crust and marginal areas of deep (12–20 km) magnetic intrusions. Based on the findings, new promising areas to prospect for gold deposits are proposed. In particular, it was concluded that the potential to host gold mineralization was underestimated for the western part of the ring structure south of the Albazino deposit.

—Magnetic and density depth models were calculated for the Malmyzh, Pony-Muli, and Anadzhakan porphyry-copper ore clusters emplaced in the northern part of the Middle Amur sedimentary basin. Based on analysis of anomalous magnetic field (magnetic model) data, a magmatogenic ring structure determining spatial patterns in localization of porphyry-copper mineralization in the Malmyzh and Pony-Muli ore clusters was established. It is shown that similar structures in the anomalous magnetic field are reported for many porphyry copper deposits. The area of the identified geologic structure can be considered as a high-potential region for detection of goldcopper-porphyry ore mineralization. Within the ring structure, perspective areas containing granitoid and diorite intrusions developed along its periphery and seated beneath the Middle Amur basin sedimentary cover can also be identified. Geophysical depth models are calculated for individual ore clusters with Au–Cu porphyry mineralization, to determine subsurface lithology and structures that may be useful for assessing regional ore potential and deducing areas for metallogenic exploration. The geophysical data-based deep subsurface model for the Malmyzh ore cluster is found to be consistent with the integrated petrological models developed by Richards and Sillitoe for giant Cuporphyry deposits.