Background: Multi-drug resistant tuberculosis has emerged as a significant problem with the resurfacing of tuberculosis and thus the need to use the second line drugs with the resultant increased incidence of adverse effects. We discuss the effect of second line aminoglycoside antitubercular drugs on the hearing status of MDR-TB patients.

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The data on the elastic scattering cross-section (CS) and vector analyzing power (VAP ) of 6,7 Li incident on 12 C, 26 Mg, 58 Ni and 120 Sn nuclei are analyzed in terms of an optical model (OM) potential, the real part of which is generated from a realistic two-nucleon interaction using the energy-density functional (EDF) formalism. The EDF-generated real part of the potential is non-monotonic (NM) in nature. This NM real potential part, without any renormalization, along with an empirically determined imaginary part and spin-orbit potential, embodying the underlying physics of projectile excitation, can successfully account for both CS and VAP data in all four cases. This investigation, for the first time, using the simple OM analysis accounts well for the opposite signs of the VAP data of elastically scattered 6,7 Li by 58 Ni at E lab ≈ 20 MeV and by 120 Sn at E lab = 44 MeV. The ramification of successfully describing the data by the EDF-generated potential to the equation of state of nuclear matter is discussed.

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