MEDICINA y SEGURIDAD del trabajo Octubre -diciembre 2014 Med Segur Trab (Internet) 2014 60 (237) AbstractIntroduction: PBDEs are potentially dangerous substances released during the e-waste recycling processes. Scientific evidence relates PBDEs with adverse health outcomes like cancer, endocrine disruptions and problems in the offspring. A high concentration of PBDEs has been found on biological samples (serum, hair, breast milk and umbilical cord) from exposed workers, so their exposure could imply a potential risk on workers health. Aim:To summarize the evidence between exposure to PBDEs contained in e-waste and adverse health outcomes on recycling industry workers. Materials and methods:A systematic review was done among the scientific literature published between 2003 and 2013 in seven data bases using Medical Subject Headings (MeSH) terms.Results: 301 articles were evaluated and 20 were included in the review. 65% were from China, 80% had a cross-sectional design. We assessed evidence of association between exposure to e-waste and levels of PBDEs in several biological samples. Workers showed high levels in the DNA damage markers. The effects from the exposure to PBDEs on the thyroid function were not consistent. Conclusions:Findings from most studies shows a correlation between the exposure to PBDEs and the alteration of the biological parameters on the recycling industry workers, but our ability to assess temporality associations was limited by the small number of prospective and longitudinal studies. Conventional industrial hygiene improvements in e-waste recycling facilities may reduce the exposure on workers to PBDEs. Med Segur Trab (Internet) 2014; 60 (237) 714-741Key words: PBDEs, e-waste, occupational exposure. ResumenIntroducción: Los PBDEs son sustancias potencialmente peligrosas liberadas del reciclaje de e-waste. La evidencia científica implica a los PBDEs en alteraciones en la salud como cáncer, alteraciones endocrinas y problemas en la descendencia. Se han encontrado elevadas concentraciones en muestras biológicas (suero, pelo, leche materna y cordón umbilical) de los trabajadores expuestos, por lo que su exposición implicaría un potencial riesgo para la salud para los trabajadores y su descendencia.Objetivo: Identificar la evidencia existente entre exposición a PBDEs contenidos en e-waste y los daños sobre la salud en trabajadores de la industria del reciclaje. Material y métodos:Se realizó una revisión sistemática de la literatura científica publicada entre 2003 y 2013, en siete bases de datos mediante términos MeSH. Las referencias se cribaron en función de los objetivos.Resultados: Se recuperaron 301 artículos y se incluyeron en la revisión 20. El 65% fueron realizados en China, el 80% respondían a un diseño transversal. Los estudios evidencian una asociación entre exposición a PBDEs y los niveles de PBDEs en distintas muestras biológicas. Los trabajadores presentaron mayores niveles de marcadores de daño al DNA. Los efectos de la exposición a PBDEs sobre la función tiroidea no fueron ...
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