Hirsutism affects a woman's social and quality of life in our society. The burden and magnitude of this effect vary from population to population. A local study was designed to determine the burden on our population. The Objective of this Cross-Sectional study was to determine the frequency of very large and extremely large effects on quality of life using Dermatology Life Quality Index (DLQI) in hirsute women presenting to Jinnah Hospital,Lahore. This study was conducted at the Outpatient Department of dermatology Jinnah hospital Lahore from 13th May 2014 to 12th November 2014. Females with hirsutism and age ranging from 18 to 49 years were included in the study. Hirsutism was labeled if the woman had Ferriman-Gallway (F-G) score ≥ 8 or one area score equal to 4, determined by clinical examination. Quality of life was determined using Dermatology Life Quality Index and waslabeled as having a very large and extremely large effect if DLQI scores were 11-20 and 21-30, respectively. The marital and educational status will be used to stratify data and dig out effect modification. Two hundred twenty patients included in our study had a mean age of 26.38± 5.58 years ranging from 12 to 42 years. The mean Ferriman-Gallway score was 15.45± 3.5, while the mean DLQI score was 18± 5.09. Diagnosis of included women was Hyperprolactinemia (4/220, 1.8%), Congenital Adrenal Hyperplasia (5/220, 2.3%), Ovarian Tumors (8/220, 3.6%), Polycystic Ovarian Disease (135/220, 61.4%) and others (68/220, 30.9%). 97% of the included patients had some formal education. 124 (56.4%) were Unmarried, 94 (42.7%) were married, while 2 (0.9%) were divorced. On DLQI, an Extremely Large Effect was present in 85 (38.6%), a Very Large effect in 115 (52.3%) while Small Effect was observed in 20 patients. There is no effect of cause or diagnosis, marital status, or educational status of thesampled population. It is concluded that the frequency of Extremely Large Effect and Very  Large effect wasobserved in more than half of the study population with hirsutism. The high burden of Extremely Large Effect on quality of life necessitates emotional and psychological rehabilitation as well as pharmacological and cosmetic methods in treating these patients.

This cross-sectional study investigated the incidence of post-inflammatory hyperpigmentation, hirsutism, and photosensitivity associated with using over-the-counter whitening creams in the local population. A total of 699 participants from the Gulab devi teaching hospital Lahore from 1 January 2022 to 31 December 2022 were included in the study. Data was collected through face-to-face structured questionnaires, capturing demographic information, whitening cream usage patterns, and reported side effects. Descriptive statistics were employed to analyze the data. The results revealed that most participants were female (59.23%) and fell within the age group of 26-35 years (35.77%). Type III (Light to Medium) skin was the most common, with 210 participants (30.06%). Type IV (Medium to Olive) skin followed closely, with 240 participants (34.31%). Type V (Dark Brown) skin was represented by 128 participants (18.34%)Regarding whitening cream usage, the most common frequency reported was once daily (45.64%), and a significant proportion of participants had been using the cream for less than 6 months (31.04%). The reported incidence of side effects demonstrated that post-inflammatory hyperpigmentation was the most prevalent (12.45%), followed by hirsutism (7.01%) and photosensitivity (4.43%). The study highlights the importance of public awareness regarding the potential risks of using over-the-counter whitening creams. It emphasizes the need for tailored recommendations based on individual skin types and the promotion of safer alternatives for achieving desired skin appearance and health. In conclusion, this study provides valuable insights into the demographic characteristics, whitening cream usage patterns, and reported side effects among individuals using over-the-counter whitening creams in the local population. It is a foundation for raising awareness, promoting informed decision-making, and encouraging safer skincare practices to enhance skin health and well-being.

Systemic treatment for psoriasis can be effective but have more risk of infection especially in old age groups. The aim of this study is to assess the infection risk in older patients with psoriasis on systemic therapy. A total of 639 patients were included in the study those were taking systemic therapy for psoriasis for last 6 months. They were divided into two groups. Group A with younger patients whereas the Group B had the older patients. Data was gathered and analyzed. Both groups were compared with respect to the incidence of infection. The results showed that that the group B had significantly high frequency of infection compared to the Group A. In conclusion, the assessment of infection risk in older patients with psoriasis who are receiving systemic therapies is crucial to ensure that patients receive the most appropriate and effective treatment while minimizing the risk of infections and other adverse events.