The study has focused on the retrospective analysis of cases of coexisting congenital aortic stenosis (AS) and pulmonary artery stenosis (PS) in dogs.The research included 5463 dogs which were referred for cardiological examination (including clinical examination, ECG and echocardiography) between 2004 and 2014. Aortic stenosis and PS stenosis were detected in 31 dogs. This complex defect was the most commonly diagnosed in Boxers -7 dogs, other breeds were represented by: 4 cross-breed dogs, 2 Bichon Maltais, 3 Miniature Pinschers, 2 Bernese Mountain Dogs, 2 French Bulldogs, and individuals of following breeds: Bichon Frise, Bull Terrier, Czech Wolfdog, German Shepherd, Hairless Chinese Crested Dog, Miniature Schnauzer, Pug, Rottweiler, Samoyed, West Highland White Terrier and Yorkshire Terrier. In all the dogs, the murmurs could be heard, graded from 2 to 5 (on a scale of 1-6). Besides, in 9 cases other congenital defects were diagnosed: patent ductus arteriosus, mitral valve dysplasia, pulmonary or aortic valve regurgitation, tricuspid valve dysplasia, ventricular or atrial septal defect. The majority of the dogs suffered from pulmonary valvular stenosis (1 dog had supravalvular pulmonary artery stenosis) and subvalvular aortic stenosis (2 dogs had valvular aortic stenosis).Conclusions and clinical relevance -co-occurrence of AS and PS is the most common complex congenital heart defect. Boxer breed was predisposed to this complex defect. It was found that coexisting AS and PS is more common in male dogs and the degree of PS and AS was mostly similar.

SummaryArrhythmogenic right ventricular cardiomyopathy (ARVC) is described as a disease that has an autosomal dominant trait with reduced penetrance, that appears in dogs between two and eight years of age. Boxers are predisposed to ARVC. Some of the symptoms of ARVC are fainting, attacks of tachycardia -especially vetnricular tachycardia and sudden cardiac death. The aim of the study was to estimate the usefulness of 24-h Holter monitoring and the level of troponin I (cTnl) in examining the treatment of Boxers with ARVC. 24-h Holter monitoring and plasma concentrations of cTnI were carried out every three months after introducing anti-arrhythmic treatment (metoprolol prolongatum, sotalol or amiodaron). There was a significant correlation between the number of ventricular premature complexes (VPC) over a 24-h period and the level of cTnl. No correlation was found between the appearance of monitoring ventricular tachycardia (VT) and the level of cTnl. The presented results show the possibility to use cTnl to evaluate the efficacy of antiarrhythmia treatment in dogs with ARVC. Keywords: Arrhythmogenic right ventricular cardiomyopathy, Holter, Troponin Aritmojenik Sağ Ventrikül Kardiyomiyopatili Boxerlarda 24 Saatlik Holter Monitorizasyon ve Troponin I Seviyesi ÖzetAritmojenik sağ ventrikül kardiyomiyopatisi (ARVC) azalmış penetrasyon ile otozomal dominant geçişe sahip bir hastalık olarak tanımlanır, köpeklerde 2 ve 8 yaş arasında görülür. Boxerlar ARVC yatkındırlar. ARVC semptomları bayılma , taşikardi atakları -özellikle ventriküler taşikardi ve ani kardiyak ölümdür. Bu çalışmanın amacı, aritmojenik sağ ventrikül kardiyomiyopatili Boxerlarda 24 saatlik Holter monitorizasyonunun ve tedavinin monitorize edilmesinde Troponin I düzeyinin yararlılıklarını değerlendirmektir. Antiaritmik tedavinin (metoprolol prolongatum, sotalol veya amiodaron) başlatılmasından sonra her 3 ayda bir Holter monitorizasyonu ve cTnI plazma konsantrasyonu uygulandı. 24 saatlik süreçte cTn1 düzeyi ile VPC sayısı arasında önemli bir korelasyon vardı. cTnI düzeyi ile VT görülmesi arasında hiçbir korelasyon bulunamadı. Sunulan sonuçlar ARVC'li olan köpeklerde antiaritmik tedavisinin etkinliğini değerlendirmede cTnI'in kullanılabilirliğini göstermektedir.

No abstract