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were readmitted in the postpartum period due to a hypertension-related diagnosis. Random forest method achieved a sensitivity of 85%, specificity of 79%, and balanced accuracy of 82% for predicting readmission. The most important variables for predicting readmission included systolic blood pressure at 48 hours postpartum and systolic blood pressure in labor. Overall, Fifteen variables were included in the final model and resulting user-friendly online clinical calculator.CONCLUSION: This validated model predicts the risk of hypertension related postpartum readmission. In contrast to prior known predictors of readmission this model uses distinct clinical variables that are easily identifiable in the medical chart. This user-friendly online clinical calculator may be used as an individualized objective tool during discharge planning, outpatient management, and perhaps those who may most benefit from daily remote patient monitoring or closer outpatient surveillance to prevent readmission.

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Objective Current recommendations for individuals with risk factors for gestational diabetes mellitus (GDM) call for screening in early pregnancy. However, there is currently no clear consensus on a specific screening modality. This study evaluates whether a hemoglobin A1c (HbA1c) screening in individuals with risk factors for gestational diabetes (GDM) could be used instead of an early 1-hour glucose challenge test (GCT). We hypothesized that the HbA1c could replace 1-hour GCT in early pregnancy evaluation Study Design This is a prospective observational trial at a single tertiary referral center of women with at least one risk factor for GDM who were screened at <16 weeks of gestation with both 1-hour GCT or HbA1c. Exclusion criteria include: previous diagnosis of diabetes mellitus, multiple gestation, miscarriage, or missing delivery information. The diagnosis of GDM was made by a 3-hour 100-g glucose tolerance test, using the Carpenter–Coustan criteria (at least two results >94, 179, 154, and 139 mg/dL for fasting, 1-, 2-, and 3-hour values, respectively), 1-hour GCT > 200 mg/dL, or HbA1c > 6.5%. Results A total of 758 patients met inclusion criteria. A total of 566 completed a 1-hour GCT and 729 had an HbA1c collected. The median gestational age at testing was 91/7 weeks (range: 40/7–156/7 weeks]. Twenty-one participants were diagnosed with GDM at <16 weeks' GA. The receiver operating characteristic (ROC) curves identified the optimal valves for a positive screen for an HbA1c > 5.6%. The HbA1c had a sensitivity of 84.2%, a specificity of 83.3%, and a false positive rate of 16.7% (p < 0.001). The area under the ROC curve for the HbA1c was 0.898. Gestational age of delivery was slightly earlier with individuals with an elevated HbA1c but no other changes in delivery or neonatal outcomes. Contingent screening improved specificity (97.7%) and decreased false positive rate to 4.4%. Conclusion HbA1c may be a good assessment in early pregnancy for gestational diabetes. Key Points