In recent decades, the decline in human fertility has become a major concern. However, unhealthy lifestyle practices, such as the use of addictive substances that contribute to infertility persist in society. Therefore, the current study reviewed the literature addressing the effects of alcohol consumption patterns on male and female fertility. Although alcohol intake is socially accepted, its detrimental influence on male and female fertility rates has been regularly observed in recent years. The findings have revealed that abstinence from chronic alcohol intake did not recover the testes from the negative effects of alcohol. Heavy drinking, defined as 8 or more glasses per week for a woman or 15 or more drinks per week for a man might impair female reproductive function. In conclusion, the implementation of an in vivo evidence strategy ranging from animal studies to preclinical ones has indicated that alcohol intake may be related to negative effects on reproductive parameters in both males and females. The present review deserves to be highlighted since it is significant for those who lead an unhealthy lifestyle, such as those who use alcohol.