The evolution of a child’s skin microbiome is associated with the development of the immune system and skin environment. As only few studies have analyzed the microbiota in young children, we investigated changes in the skin microbiota of children (158 subjects; ≤10 years old) and compared the microbiota structures between children and their mothers using 16S rRNA gene amplicon sequencing. Sample location and age were the primary factors determining a child’s skin bacterial composition, which differed significantly among the face, ventral forearm, and calf. Relative abundances of Streptococcus and Granulicatella were negatively correlated with age, and the alpha diversity at all body sites examined increased during the first 10 years of life, especially on the face. The facial bacterial composition of 10-year-old children was strongly associated with delivery mode at birth. Among mother-child pairs (50 pairs), the relative abundances of most bacterial genera in children were more similar to those of their own mothers than those of unrelated women. The data indicated that age and site were significantly associated with microbial composition and that maternal factors determine the child’s microbiome. Further research is needed to characterize the effects of maturation of the infant microbiome on health in adulthood.
While products get more challenging to repair, the right-to-repair movement aims to empower consumers in their ability to “use, modify, and repair” a device “whenever, wherever, and however” they want. Here, the best design practices and remaining challenges of three industrial sectors – namely, consumer electronics, biomedical devices, and clothing industry – are investigated in light of the right-to-repair movement. Based on literature reviews and industrial surveys, a SWOT analysis is provided for each sector, and sustainable implications for product repair readiness are drawn. Concretely, recommendations to design, develop and sell products with right-to-repair in mind are given by sector. Future directions for a more quantitative assessment and implementation of design for product repair are discussed to ensure the augmentation of the circularity and sustainability performance of products.
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