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Background: The SARS-CoV-2 and associated corona virus disease COVID-19 have been declared a pandemic having a poor prognosis among individuals with debilitating conditions and those who are immune-compromised. Current evidence is however limited on maternal and fetal transmission and pregnancy outcomes. We aimed to describe the pattern of SARS-CoV-2 infection and outcomes in a group of pregnant women followed up at a tertiary care unit in Cameroon. Methods: This was an observational study conducted over a period of 3 months (April 1 to June 30, 2020) at the Yaounde Central Hospital. All pregnant women who were tested positive for SARS-CoV-2 and who provided a signed written informed consent were included in the study. Results: Out of 83 pregnant women who presented with symptoms suspicious of COVID-19, 25 were tested positive. The median age of these women was 31 (27 -35) years. A total of 76% consulted within 6 days of onset of symptoms and 68% had a gestational age greater than 28 weeks. The most common presenting complaint was fever (88%). All 25 pregnant women who were tested positive for COVID-19 were followed up with 9/25 deliveries registered. There were two intra-uterine fetal deaths and seven live births. All the live birth babies were tested negative on Real Time-Polymerase Chain Reaction (RT-PCR) testing which was performed after birth. Conclusion: Deliverance of live and SARS-CoV-2 negative babies from COVID-19 pregnant women is possible.

Introduction: Macrosomia represents a high-risk obstetrical situation because it is at the origin of an important maternal-fetal morbidity through its numerous complications, reason for which it would put at risk the maternal-fetal vital prognosis. However, few studies have been carried out in our environment, hence the need to contextualize and update the data. Objective: Our objective was to study the epidemiological, clinical and therapeutic aspects of the delivery of macrosomia at the Gynaecological-Obstetric and Paediatric Hospital of Yaoundé. Methodology: This was a descriptive cross-sectional study with prospective data collection at the Gynaecological-Obstetric and Paediatric Hospital in Yaoundé. The recruitment period was spread over 4 months, from 03 January to 07 May 2021. Thus, we included in our study, women who delivered a macrosomic newborn and gave their informed consent for the study. The data collected were analyzed using SPSS version 22.0 software. Results: In total, we included 52 participants. We obtained a frequency of 6.23% of macrosomal deliveries at the HGOPY. The most represented age group was between 25 and 30 years for an average age of 29 years.Diabetes was found in a small proportion (1.9%), Obesity was found in 12% of cases. Induction of labour was necessary in 13% of cases. Uterine heights between 34 and 37 cm were predominant in 56% of cases. Multiparous women were the most common in 32% of cases, and postterm in 7% of cases. The most common presentation was cephalic at 92%. Caesarean section was necessary in 37% of cases and occurred mostly in emergency at 85% and the use of oxytocin was the majority. Complications at delivery were dominated by perineal lesions in 70% of cases and delivery haemorrhage in 60% of cases. We observed 92% of macrosomic newborns with a weight between 4000 and 4499 grams. Male sex was predominant in 72%. Fetal complications occurred in 11% of cases and were dominated by hypoglycemia and fetal death in utero. We did not record any neonatal or maternal deaths. Conclusion: Macrosomia is common in our study site. It mainly concerns women from the western region, with an average age of 30 years. The rate of caesarean section is high allowing the birth of a boy in the majority of cases. Maternal complications are dominated by perineal lesions and delivery haemorrhage, fetal complications by in utero fetal death and hypoglycaemia. Perinatal mortality is high.

Les auteurs rapportent une grossesse de haut rang (quadruplés) dont le nombre de fœtus n'a été découvert que pendant l'accouchement par voie vaginale. Faute de moyens, la parturiente reçue en phase active du travail n'a pas pu bénéficier de la césarienne d'urgence indiquée pour présentation en siège du premier jumeau. Ce n'est qu'après l'accouchement du deuxième fœtus que les deux derniers quadruplés ont été successivement découverts. Les difficultés et les pièges contextuels de la prise en charge des grossesses multiples sont passés en revue. Ce cas rappelle au personnel des salles d'accouchement la possibilité d'erreur de diagnostique sur les résultats d'échographies présentés par les parturientes.

Since its appearance in China in December 2019, COVID-19 which is caused by the SARS-CoV-2 virus has become a real global health problem. Pregnant women are not immune to this novel infection, which makes it difficult for proper management of pregnancy and childbirth. Authors present here the first case of childbirth in Cameroon of a 19-year-old adolescent tested positive for COVID-19.