Background: Patellofemoral pain syndrome (PFPS) is anterior knee pain that is increased by ascending or descending stairs or prolonged sitting with bent knees in absence of significant structural changes. The current study aims to assess the outcome of arthroscopic denervation of the patella using a radiofrequency ablation device in the management of resistant patellofemoral pain in absence of malalignment and patellofemoral maltracking. Methods: This prospective study was conducted in Orthopedic Surgery department at Benha University hospital on 25 patients with resistant patellofemoral pain syndrome. Results: one year Post-operatively, there was high statistically significant improvement in VAS on comparing preoperative (p<0.001).There were no significant changes in pain VAS 6 months postoperatively and at 1year postoperatively (p>0.05). Six months Post-operatively, there was high statistically significant improvement in Kujala on comparing preoperative (p<0.001). Also, one year Post-operatively, there was high statistically significant improvement in Kujala on comparing preoperative (p<0.001). One year Post-operatively, there was high statistically significant improvement in Lysholm score on comparing preoperative (p<0.001). There were no significant changes in Lysholm score 6 months postoperatively and at 1year postoperatively (p>0.05).Complications were found in eleven cases in our study, nine cases complicated by quadriceps muscle atrophy, one case with DVT and one case had anterosuperomedial (ASM) portal synovial sinus. Conclusion: Arthroscopic patellar denervation is a simple procedure that yields good results, improved patient satisfaction, and leads to nonsignificant complications in the management of resistant patellofemoral pain syndrome.

Background: Osteoarthritis (OA) is most prevalent type of arthritis, which significantly affects the patient's mobility complex.The aim to evaluate the evidence from the literature regarding the superiority of platelet-rich plasma (PRP), hyaluronic acid (HA), or corticosteroids (CS) over each other's. Methods: An electronic search was conducted between January 2010 to March 2021 in different databases; PubMed, SCOPUS, Web of Science, and Cochrane Central Register of Controlled Trials (CENTRAL). The articles included were the randomized, nonrandomized trials that were published in English with full text available. Results: From a total 6912 screened citations, thirty studies met our inclusion criteria with a total 3303 cases. Most on included studies (N=13) compared platelet-rich plasma to hyaluronic acid and six studies compared hyaluronic acid to cortico-steroids, four studies compared hyaluronic acid to hyaluronic acid + cortico-steroids , one study compared platelet-rich plasma to cortico-steroids and another study compared plateletrich plasma to hyaluronic acid, cortico-steroids. Regarding platelet-rich plasma compared to hyaluronic acid, evidence favored platelet-rich plasma over hyaluronic acid in majority of studies, the effect of platelet-rich plasma lasted longer up to 12 months, and it might be extended to 18 months if intra-osseous injection would be considered. On the other hand, hyaluronic acid should moderate efficacy over cortico-steroids injection but its effects survived only up to six months. Conclusion;platelet-rich plasma is most effective type on the long term and it provides pain relief up to 12 months especially in cases with low grades osteoarthritis and young age patients.