Analgesic medicines are the most regularly prescribed pharmaceuticals globally. The goal of this project is to learn about and improve analgesic use practices through an education campaign. Materials and Procedures: This cross-sectional, online survey was conducted for 340 respondents in Derna City Libya region between 15 April 2022 and two November 2022. Result: Males were 49 (14.4%) and females were 291 (85.6%), the Mean & S.D (1.86, 0.352), ages 10 - 65 years old, the Mean & S.D (1.86, 0.352), (3.92, 2.082). The greatest percentage of excellent at the economic level is 153 (45.0%). The lowest score for superb is 6 (1.8%), followed by 45% for a decent scenario, 35% for a not-so-poor situation, and 7.1% for a horrible one. The percentage of university graduates is 203 (59.7%), whereas the percentage of illiterate people is 3 (0.9%). The P-Value of understanding the adverse effects of using analgesics regularly (0.000 0.05), the correlation is significant for there is a link between knowledge and educational level, the relationship between knowledge and educational level demonstrates that a p-value greater than 0.05 indicates that there is no relationship between knowledge and educational level. Conclusion: No matter how high a person's education level is, it does not substitute for understanding the usage of analgesic drugs and there's no correlation between a scientific degree and citizens' understanding of the hazards of utilizing analgesic drugs without a prescription.