The overall success of a periapical surgery is assessed in terms of regeneration of functional periradicular tissues. The regenerative potential of platelets has been well documented. This article describes the use of concentrated growth factors (CGF), a new family of autologous platelet concentrates, as a sole material for bone regeneration after periapical surgery. 32- and 35-year-old female patients diagnosed with Ellis Class IV, an open apex in 11 with apical periodontitis in 11 and 12 and previously root canal-treated 31 and 41 with a chronic apical abscess, respectively, were managed with endodontic surgery. Subsequent to apicectomy and retrograde filling, the CGF fibrin block and membrane were used before suturing. There was uneventful healing during the immediate post-op and the subsequent follow-up periods. CGF is produced by a differential centrifugation process that results in the formation of a denser fibrin matrix richer in growth factors than those observed in PRF. Reasonable osseous healing was seen as early as 6-month follow-up, thereby recommending the use of CGF as an alternative to bone grafts and membranes in extensive periapical lesions to enhance bone regeneration and to decrease the healing time.

Introduction:Dental erosion is defined as the loss of tooth structure due to chemical process that does not involve bacteria. The management of such a condition calls for a comprehensive approach to identifying the cause and treating it.Aim:The aim of this study is to comparatively evaluate the role of grape seed extract (GSE) and cranberry extract (CE) in preventing dental erosion using optical emission spectrometry.Materials and Methods:Prepared enamel specimens were subjected to the erosive challenge using HCl for 10 s, followed by immersion in experimental natural groups and control fluoride group for 30 s and artificial saliva for 60 min. This cycle was repeated three times. The amounts of calcium and phosphorous present in the acid solution after 1st, 2nd, and 3rd erosive challenges were determined for each group using induced coupled plasma-optical emission spectrometry.Results:The cumulative calcium and phosphorous release after the 1st, 2nd, and 3rd erosive challenges were found to be the least in SnF2 group, followed by GSE group and then in CE group.Conclusion:The protective of GSE and CE was inferior to the gold standard control group of stannous fluoride role, against enamel erosion. GSE showed better remineralizing effect; however, there was no statistically significant difference between the two groups.

Introduction: The postendodontic pain is caused by either microbial, mechanical, or chemical factors or combinations of these. The incidence of postoperative pain ranges from 1.4% to 53%. The management of postendodontic pain is a crucial factor for a successful practitioner. Cryotherapy is a new therapeutic option applied in sports medicine and surgery for the management of pain and for postoperative care. Aim: The purpose of this study was to evaluate and to compare the effect of intracanal cryotreated sodium hypochlorite and room temperature sodium hypochlorite on postoperative pain after root canal treatment. Materials and Methods: Sixty-four patients were selected according to inclusion criteria and baseline score was recorded. After obtaining consent, the access cavity was opened under local anesthesia. On the completion of cleaning and shaping, the patients were randomly divided into two groups: Group A: Normal Room temperature NaOCl and Group B: Cryotreated NaOCl (2°C–4°C), each of the canals further received 20 ml of the respective irrigants based on the groups allocated. The final rinse was done with saline, and canals were dried and obturated in the same appointment. Postoperative visual analogue scale pain levels were recorded at 6, 24, and 48 h over the phone. Results: The data were analyzed using SPSS software. The results of the present study showed that cryotherapy group showed a statistically significant reduction in postoperative pain levels at all tested time intervals and reduced analgesic intake at 6 h postoperatively. Conclusion: Cryotherapy could be used as an easy and cost-effective technique for controlling postendodontic pain in the day-to-day clinical practice.

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